Emerging Fungal Infections and Cutaneous Manifestations in Immunosuppressed Patients

Jeffrey Alex Varghese, Samantha Guhan, Lida Zheng*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: The goal of this paper is to describe the most pertinent fungal infections found in immunocompromised hospitalized patients and their cutaneous presentations. Recent Findings: Opportunistic fungi and severe forms of systemic fungal infections are predominantly seen in immunocompromised patients including those with solid organ and stem cell transplant, hematologic malignancies, and acquired immunodeficiency syndrome. Some fungal infections can present with classic skin lesions that can help clinicians to make the appropriate diagnosis and to initiate appropriate antifungal coverage. Summary: Recognition of cutaneous findings in immunocompromised patients within the hospital is crucial guiding appropriate management of care. Prophylaxis for fungal infections is common in those with prolonged immunosuppression, and while newer regimens have broader coverage, emerging fungal infections still occur in this vulnerable population.

Original languageEnglish (US)
Pages (from-to)69-81
Number of pages13
JournalCurrent Dermatology Reports
Volume12
Issue number2
DOIs
StatePublished - Jun 2023

Keywords

  • Antifungal treatment
  • Cutaneous manifestations
  • Fungal infections
  • Immunocompromised
  • Skin lesions
  • Solid organ transplant

ASJC Scopus subject areas

  • Dermatology

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