Empowering genomic medicine by establishing critical sequencing result data flows: The eMERGE example

Samuel Aronson*, Lawrence Babb, Darren Ames, Richard A. Gibbs, Eric Venner, John J. Connelly, Keith Marsolo, Chunhua Weng, Marc S. Williams, Andrea L. Hartzler, Wayne H. Liang, James D. Ralston, Emily Beth Devine, Shawn Murphy, Christopher G. Chute, Pedro J. Caraballo, Iftikhar J. Kullo, Robert R. Freimuth, Luke V. Rasmussen, Firas H. WehbeJosh F. Peterson, Jamie R. Robinson, Ken Wiley, Casey Overby Taylor

*Corresponding author for this work

    Research output: Contribution to journalArticle

    4 Citations (Scopus)

    Abstract

    The eMERGE Network is establishing methods for electronic transmittal of patient genetic test results from laboratories to healthcare providers across organizational boundaries. We surveyed the capabilities and needs of different network participants, established a common transfer format, and implemented transfer mechanisms based on this format. The interfaces we created are examples of the connectivity that must be instantiated before electronic genetic and genomic clinical decision support can be effectively built at the point of care. This work serves as a case example for both standards bodies and other organizations working to build the infrastructure required to provide better electronic clinical decision support for clinicians.

    Original languageEnglish (US)
    Pages (from-to)1375-1381
    Number of pages7
    JournalJournal of the American Medical Informatics Association
    Volume25
    Issue number10
    DOIs
    StatePublished - Oct 1 2018

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    Clinical Decision Support Systems
    Point-of-Care Systems
    Medicine
    Health Personnel

    ASJC Scopus subject areas

    • Health Informatics

    Cite this

    Aronson, S., Babb, L., Ames, D., Gibbs, R. A., Venner, E., Connelly, J. J., ... Overby Taylor, C. (2018). Empowering genomic medicine by establishing critical sequencing result data flows: The eMERGE example. Journal of the American Medical Informatics Association, 25(10), 1375-1381. https://doi.org/10.1093/jamia/ocy051
    Aronson, Samuel ; Babb, Lawrence ; Ames, Darren ; Gibbs, Richard A. ; Venner, Eric ; Connelly, John J. ; Marsolo, Keith ; Weng, Chunhua ; Williams, Marc S. ; Hartzler, Andrea L. ; Liang, Wayne H. ; Ralston, James D. ; Devine, Emily Beth ; Murphy, Shawn ; Chute, Christopher G. ; Caraballo, Pedro J. ; Kullo, Iftikhar J. ; Freimuth, Robert R. ; Rasmussen, Luke V. ; Wehbe, Firas H. ; Peterson, Josh F. ; Robinson, Jamie R. ; Wiley, Ken ; Overby Taylor, Casey. / Empowering genomic medicine by establishing critical sequencing result data flows : The eMERGE example. In: Journal of the American Medical Informatics Association. 2018 ; Vol. 25, No. 10. pp. 1375-1381.
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    abstract = "The eMERGE Network is establishing methods for electronic transmittal of patient genetic test results from laboratories to healthcare providers across organizational boundaries. We surveyed the capabilities and needs of different network participants, established a common transfer format, and implemented transfer mechanisms based on this format. The interfaces we created are examples of the connectivity that must be instantiated before electronic genetic and genomic clinical decision support can be effectively built at the point of care. This work serves as a case example for both standards bodies and other organizations working to build the infrastructure required to provide better electronic clinical decision support for clinicians.",
    author = "Samuel Aronson and Lawrence Babb and Darren Ames and Gibbs, {Richard A.} and Eric Venner and Connelly, {John J.} and Keith Marsolo and Chunhua Weng and Williams, {Marc S.} and Hartzler, {Andrea L.} and Liang, {Wayne H.} and Ralston, {James D.} and Devine, {Emily Beth} and Shawn Murphy and Chute, {Christopher G.} and Caraballo, {Pedro J.} and Kullo, {Iftikhar J.} and Freimuth, {Robert R.} and Rasmussen, {Luke V.} and Wehbe, {Firas H.} and Peterson, {Josh F.} and Robinson, {Jamie R.} and Ken Wiley and {Overby Taylor}, Casey",
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    Aronson, S, Babb, L, Ames, D, Gibbs, RA, Venner, E, Connelly, JJ, Marsolo, K, Weng, C, Williams, MS, Hartzler, AL, Liang, WH, Ralston, JD, Devine, EB, Murphy, S, Chute, CG, Caraballo, PJ, Kullo, IJ, Freimuth, RR, Rasmussen, LV, Wehbe, FH, Peterson, JF, Robinson, JR, Wiley, K & Overby Taylor, C 2018, 'Empowering genomic medicine by establishing critical sequencing result data flows: The eMERGE example', Journal of the American Medical Informatics Association, vol. 25, no. 10, pp. 1375-1381. https://doi.org/10.1093/jamia/ocy051

    Empowering genomic medicine by establishing critical sequencing result data flows : The eMERGE example. / Aronson, Samuel; Babb, Lawrence; Ames, Darren; Gibbs, Richard A.; Venner, Eric; Connelly, John J.; Marsolo, Keith; Weng, Chunhua; Williams, Marc S.; Hartzler, Andrea L.; Liang, Wayne H.; Ralston, James D.; Devine, Emily Beth; Murphy, Shawn; Chute, Christopher G.; Caraballo, Pedro J.; Kullo, Iftikhar J.; Freimuth, Robert R.; Rasmussen, Luke V.; Wehbe, Firas H.; Peterson, Josh F.; Robinson, Jamie R.; Wiley, Ken; Overby Taylor, Casey.

    In: Journal of the American Medical Informatics Association, Vol. 25, No. 10, 01.10.2018, p. 1375-1381.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Empowering genomic medicine by establishing critical sequencing result data flows

    T2 - The eMERGE example

    AU - Aronson, Samuel

    AU - Babb, Lawrence

    AU - Ames, Darren

    AU - Gibbs, Richard A.

    AU - Venner, Eric

    AU - Connelly, John J.

    AU - Marsolo, Keith

    AU - Weng, Chunhua

    AU - Williams, Marc S.

    AU - Hartzler, Andrea L.

    AU - Liang, Wayne H.

    AU - Ralston, James D.

    AU - Devine, Emily Beth

    AU - Murphy, Shawn

    AU - Chute, Christopher G.

    AU - Caraballo, Pedro J.

    AU - Kullo, Iftikhar J.

    AU - Freimuth, Robert R.

    AU - Rasmussen, Luke V.

    AU - Wehbe, Firas H.

    AU - Peterson, Josh F.

    AU - Robinson, Jamie R.

    AU - Wiley, Ken

    AU - Overby Taylor, Casey

    PY - 2018/10/1

    Y1 - 2018/10/1

    N2 - The eMERGE Network is establishing methods for electronic transmittal of patient genetic test results from laboratories to healthcare providers across organizational boundaries. We surveyed the capabilities and needs of different network participants, established a common transfer format, and implemented transfer mechanisms based on this format. The interfaces we created are examples of the connectivity that must be instantiated before electronic genetic and genomic clinical decision support can be effectively built at the point of care. This work serves as a case example for both standards bodies and other organizations working to build the infrastructure required to provide better electronic clinical decision support for clinicians.

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