Abstract
An improved three-step synthesis has been developed for the preparation of N-docosanoyl-D-valine tert.-butylamide. This gas chromatographic phase, and the corresponding previously described enantiomeric L-valine phase, which bring about a reversal in the elution patterns of antipodes, were found to perform with comparable accuracy and precision when used for the gas chromatographic analysis of D- and L-leucine mixtures. This reversal of the elution pattern of enantiomeric eluates offers a number of hitherto unattainable advantages in both qualitative and quantitative gas chromatographic analyses of enantiomer mixtures.
Original language | English (US) |
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Pages (from-to) | 153-159 |
Number of pages | 7 |
Journal | Journal of Chromatography A |
Volume | 169 |
Issue number | C |
DOIs | |
State | Published - Feb 1 1979 |
ASJC Scopus subject areas
- Analytical Chemistry
- Biochemistry
- Organic Chemistry