Enantiomeric phases in analytical gas chromatography

William A. Bonner*, Neal E. Blair

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Scopus citations


An improved three-step synthesis has been developed for the preparation of N-docosanoyl-D-valine tert.-butylamide. This gas chromatographic phase, and the corresponding previously described enantiomeric L-valine phase, which bring about a reversal in the elution patterns of antipodes, were found to perform with comparable accuracy and precision when used for the gas chromatographic analysis of D- and L-leucine mixtures. This reversal of the elution pattern of enantiomeric eluates offers a number of hitherto unattainable advantages in both qualitative and quantitative gas chromatographic analyses of enantiomer mixtures.

Original languageEnglish (US)
Pages (from-to)153-159
Number of pages7
JournalJournal of Chromatography A
Issue numberC
StatePublished - Feb 1 1979

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry


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