Enantioselective Syntheses of Yohimbine Alkaloids: Proving Grounds for New Catalytic Transformations

Eric R. Miller, Karl A. Scheidt*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations

Abstract

The total synthesis of bioactive alkaloids is an enduring challenge and an indication of the state of the art of chemical synthesis. With the explosion of catalytic asymmetric methods over the past three decades, these compelling targets have been fertile proving grounds for enantioselective bond forming transformations. These activities are summarized herein both to highlight the power and versatility of these methods and to instill future inspiration for new syntheses of these privileged natural products.

Original languageEnglish (US)
Pages (from-to)1217-1230
Number of pages14
JournalSynthesis (Germany)
Volume54
Issue number5
DOIs
StatePublished - Jan 4 2022

Keywords

  • alkaloids
  • asymmetric catalysis
  • asymmetric synthesis
  • catalysis
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Organic Chemistry

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