Abstract
The total synthesis of bioactive alkaloids is an enduring challenge and an indication of the state of the art of chemical synthesis. With the explosion of catalytic asymmetric methods over the past three decades, these compelling targets have been fertile proving grounds for enantioselective bond forming transformations. These activities are summarized herein both to highlight the power and versatility of these methods and to instill future inspiration for new syntheses of these privileged natural products.
Original language | English (US) |
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Pages (from-to) | 1217-1230 |
Number of pages | 14 |
Journal | Synthesis (Germany) |
Volume | 54 |
Issue number | 5 |
DOIs | |
State | Published - Jan 4 2022 |
Keywords
- alkaloids
- asymmetric catalysis
- asymmetric synthesis
- catalysis
- total synthesis
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry