Endobronchial valve treatment for prolonged air leaks of the lung: A case series

Colin T. Gillespie, Daniel H. Sterman, Robert J. Cerfolio, Daniel Nader, Michael S. Mulligan, Richard A. Mularski, Ali I. Musani, John C. Kucharczuk, H. Xavier Gonzalez, Steven C. Springmeyer

Research output: Contribution to journalArticlepeer-review

85 Scopus citations


Purpose An endobronchial valve developed for treatment of severe emphysema has characteristics favorable for bronchoscopic treatment of air leaks. We present the results of a consecutive case series treating complex alveolopleural fistula with valves. Description Patients with air leaks that persisted after treatment gave consent and compassionate use approval was obtained. Bronchoscopy with balloon occlusion was used to identify the airways to be treated. IBV Valves (Spiration, Redmond, WA) were placed after airway measurement. Evaluation During a 15-month period, 8 valve placement procedures were performed in 7 patients and all had improvement in the air leak. The median duration of air leakage was 4 weeks before and 1 day after treatment, with a mean of 4.5 days. Discharge within 2 to 3 days of the procedure occurred in 57% of the patients. A median of 3.5 valves (mode, 2.4) were used, and all valve removals were successful. There were no procedural or valve-related complications. Conclusions Removable endobronchial valves appear to be a safe and effective intervention for prolonged air leaks.

Original languageEnglish (US)
Pages (from-to)270-273
Number of pages4
JournalAnnals of Thoracic Surgery
Issue number1
StatePublished - Jan 2011

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery


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