Endocrine manifestations of craniopharyngioma

Isil Halac; Donald Zimmerman

doi:10.1007/s00381-005-1246-x

Endocrine manifestations of craniopharyngioma

Isil Halac, Donald Zimmerman^*

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Review article › peer-review

68 Scopus citations

Abstract

Rationale: Due to the proximity of craniopharyngiomas to the hypothalamus and pituitary gland, most children and adolescents presenting with these tumors will exhibit significant endocrine dysfunction. After treatment, these impairments can become a major cause of morbidity and mortality. Methods: The postoperative course of children undergoing surgery for craniopharyngioma is reviewed. Conclusion: Even if hormone levels seem to be adequate in the short term after treatment, deficiencies may develop over years and need to be monitored closely.

Original language	English (US)
Pages (from-to)	640-648
Number of pages	9
Journal	Child's Nervous System
Volume	21
Issue number	8-9
DOIs	https://doi.org/10.1007/s00381-005-1246-x
State	Published - Aug 2005

Keywords

Child
Craniopharyngioma/surgery
Desmopressin/administration and dosage
Growth hormone/deficiency
Hypopituitarism/drug therapy
Pituitary function tests
Pituitary neoplasms/surgery
Postoperative complications/drug therapy

ASJC Scopus subject areas

Clinical Neurology
Pediatrics, Perinatology, and Child Health

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10.1007/s00381-005-1246-x

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title = "Endocrine manifestations of craniopharyngioma",

abstract = "Rationale: Due to the proximity of craniopharyngiomas to the hypothalamus and pituitary gland, most children and adolescents presenting with these tumors will exhibit significant endocrine dysfunction. After treatment, these impairments can become a major cause of morbidity and mortality. Methods: The postoperative course of children undergoing surgery for craniopharyngioma is reviewed. Conclusion: Even if hormone levels seem to be adequate in the short term after treatment, deficiencies may develop over years and need to be monitored closely.",

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AU - Halac, Isil

AU - Zimmerman, Donald

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AB - Rationale: Due to the proximity of craniopharyngiomas to the hypothalamus and pituitary gland, most children and adolescents presenting with these tumors will exhibit significant endocrine dysfunction. After treatment, these impairments can become a major cause of morbidity and mortality. Methods: The postoperative course of children undergoing surgery for craniopharyngioma is reviewed. Conclusion: Even if hormone levels seem to be adequate in the short term after treatment, deficiencies may develop over years and need to be monitored closely.

KW - Child

KW - Craniopharyngioma/surgery

KW - Desmopressin/administration and dosage

KW - Growth hormone/deficiency

KW - Hypopituitarism/drug therapy

KW - Pituitary function tests

KW - Pituitary neoplasms/surgery

KW - Postoperative complications/drug therapy

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JO - Child's Nervous System

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ER -

Endocrine manifestations of craniopharyngioma

Abstract

Keywords

ASJC Scopus subject areas

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