Endocrine problems of adolescent pregnancy

M. E. Molitch*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


A number of changes in renal and endocrine physiology occur during pregnancy that alter hormone levels and affect a number of disease processes. Increased glomerular filtration causes an increase in hormone and substrate clearance. Increased placental steroid production causes an increase in hormone-binding globulin production, insulin resistance, and prolactinoma growth. Production of peptide hormones may cause changes in normal physiology and alter dynamic hormone testing. Placental vasopressinase increases vasopressin clearance. A number of diseases of hormone overproduction and underproduction affect pregnancy outcome and must be treated promptly by therapeutic modalities that also may affect the fetus.

Original languageEnglish (US)
Pages (from-to)649-672
Number of pages24
JournalEndocrinology and Metabolism Clinics of North America
Issue number3
StatePublished - 1993

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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