Endodermal Sinus Tumor of the Parotid Gland in a Child

Simone Treiger Sredni*, Isabela Werneck Da Cunha, Nevigolino Pereira De Carvalho Filho, Jose Magrin, Clovis Antonio Lopes Pinto, Luis Fernando Lopes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


We report a case of a 16-month-old girl with a primary endodermal sinus tumor (EST) of the parotid gland. The girl was admitted to the hospital with a left side cervical tumor with a quick growth (within 3 wk). The tumor was surgically resected. The gross examination showed a 7.0-cm hemorrhagic and fragmentized mass. Diagnosis of an EST was established on the hematoxylin and eosinstained slides from the resected material. Elevated serum alpha-fetoprotein (AFP) levels were detected and follow-up examinations of the patient did not show ESTs in other locations or other manifestations due to the tumor. The patient received chemotherapy after the surgery and remained alive without evidence of disease at the time of this writing (2 years after the diagnosis). As far as we know, this is the second report in the literature of a parotid gland's EST.

Original languageEnglish (US)
Pages (from-to)77-80
Number of pages4
JournalPediatric and Developmental Pathology
Issue number1
StatePublished - Jan 1 2004


  • Childhood cancer
  • Endodermal sinus tumor
  • Parotid gland
  • Yolk sac tumor

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pathology and Forensic Medicine


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