ENDOR of metalloenzymes

Brian M. Hoffman

doi:10.1021/ar0202565

ENDOR of metalloenzymes

Brian M. Hoffman^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

81 Scopus citations

Abstract

This Account examines the role of electron-nuclear double resonance (ENDOR) spectroscopy in furthering our understanding of how metal ions function in biological systems. It briefly describes ENDOR and electron spin-echo envelope modulation (ESEEM) spectroscopies and then illustrates the uses of ENDOR with several case studies from our own research: cytochrome c peroxidase compound ES; ribonucleotide reductase intermediate X; allylbenzene-inactivated chloroperoxidase; the role of the [4Fe-4S]⁺ cluster in enzymes of the "radical S-adenosylmethionine" superfamily; dioxygen activation by heme enzymes. Finally, it briefly considers future developments.

Original language	English (US)
Pages (from-to)	522-529
Number of pages	8
Journal	Accounts of chemical research
Volume	36
Issue number	7
DOIs	https://doi.org/10.1021/ar0202565
State	Published - Jul 1 2003

ASJC Scopus subject areas

General Chemistry

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ENDOR of metalloenzymes

Abstract

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