Endoscope-assisted posterior quadrant disconnection plus corpus callosotomy: Case report

Melissa A. LoPresti, Kathryn Wagner, Sandi Lam*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Intractable epilepsy impacts many children. Surgically resective and palliative treatments have developed to increase seizure freedom or palliate the seizure burden in those with medically refractory epilepsy. However, surgical epilepsy treatment can confer significant morbidity and death. Endoscope-assisted surgical approaches may be helpful in reducing the morbidity related to traditional open surgical approaches while allowing for good visualization of surgical targets. Here, the authors report a case utilizing an endoscope-assisted keyhole approach to perform a posterior quadrantectomy and corpus callosotomy, achieving the surgical goals of disconnection and reducing the need for large craniotomy exposure. They present the case of a 17-year-old male with medically refractory epilepsy treated with endoscope-assisted posterior quadrantectomy and corpus callosotomy through two mini-craniotomies to achieve a functional disconnection. To the authors’ knowledge, this is the first reported case of an endoscope-assisted approach for a posterior quadrantectomy for surgical epilepsy treatment in an adult or a pediatric patient. The case is reported to highlight the technical nuances and benefits of this approach in select patients as well as the expansion of applications of endoscope-assisted epilepsy surgery.

Original languageEnglish (US)
Pages (from-to)406-410
Number of pages5
JournalJournal of Neurosurgery: Pediatrics
Issue number4
StatePublished - Apr 2021


  • Endoscopic surgery
  • Epilepsy surgery
  • Minimally invasive surgery
  • Pediatric neurosurgery
  • Posterior quadrantectomy

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology


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