Endoscopic assessment of eosinophilic esophagitis

Robert T. Kavitt, Ikuo Hirano*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

Eosinophilic esophagitis (EoE) is a clinicopathologic, inflammatory disease of the esophagus with increasing prevalence. In adults, the condition presents with dysphagia and may result in food impaction. There are a number of endoscopic findings in patients with EoE that include esophageal rings, linear furrowing, white plaques, strictures, and edema. Although individually each of these features may be seen in other esophageal diseases; when combined they have a high specificity for the pathologic finding of esophageal eosinophilia. Prospective studies have identified the presence of endoscopically identified, esophageal signs in most children and adults with EoE. In this article, we highlight a number of recent studies, including the development of an endoscopic classification and grading system to describe the esophageal manifestations of EoE. We also discuss the results of randomized controlled trials with end points assessing endoscopic findings before and after diet therapy and corticosteroids. Fibrostenotic sequelae are common in patients with EoE, and a technique to measure esophageal distensibility, which has been shown to be a predictor of risk of future food impactions and need for esophageal dilation, is discussed. Endoscopic features of EoE play an important role in our current understanding of the complications of EoE and are an important component of the assessment of disease severity and treatment response.

Original languageEnglish (US)
Pages (from-to)20-25
Number of pages6
JournalTechniques in Gastrointestinal Endoscopy
Volume16
Issue number1
DOIs
StatePublished - Jan 2014

Keywords

  • Dysphagia
  • Endoscopy
  • Eosinophil
  • Eosinophilic esophagitis
  • Esophagogastroduodenoscopy
  • Gastroesophageal reflux disease

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Gastroenterology

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