Endoscopic endonasal resection of suprasellar meningiomas: The importance of case selection and experience in determining extent of resection, visual improvement, and complications

Malte Ottenhausen, Matei A. Banu, Dimitris G. Placantonakis, A. John Tsiouris, Osaama H. Khan, Vijay K. Anand, Theodore H. Schwartz*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

37 Scopus citations

Abstract

OBJECTIVE: Suprasellar meningiomas have been resected via various open cranial approaches. During the past 2 decades, the endoscopic endonasal approach has been shown to be an option in selected patients. We wished to examine the learning curve for parameters such as extent of resection, visual outcome, and complications.

METHODS: We retrospectively reviewed a consecutive series of patients in whom suprasellar meningiomas were resected via an endonasal endoscopic approach between 2005 and 2013 at our institution. After June 2008, our surgical technique matured. Using this time point, we divided our case series into 2 chronological groups, group 1 (n=8) and group 2 (n=12). This cut-off also was used to examine rates of gross total resection (GTR) and visual improvement. Case selection criteria in successful and unsuccessful cases were examined to determine important principals for case selection.

Results: Mean patient age at surgery was 57.05 years (range, 31e81 years). Mean tumor volume was 11.98 cm3 (range, 0.43L28.93 cm3). Overall, GTR was achieved in 80%, and vision improved or normalized in 14 patients (82.4%) with no occurrence of postoperative visual deterioration. Rates of GTR increased from 62.5% (group 1) to 91.7% (group 2). Visual improvement increased from 75% (group 1) to 88.9% (group 2). Rates of cerebrospinal fluid leak were 25% in group 1 and 0% in group 2. Average follow-up was 51.5 month (range, 3L96 months). -CONCLUSION: Once the learning curve is overcome, surgeons performing endonasal endoscopic resection of suprasellar meningiomas can achieve high rates of GTR with low complication rates in well-selected cases.

Original languageEnglish (US)
Pages (from-to)442-449
Number of pages8
JournalWorld neurosurgery
Volume82
Issue number3
DOIs
StatePublished - Sep 1 2014

Keywords

  • Endonasal
  • Endoscopic
  • Suprasellar meningioma
  • Transsphenoidal

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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