Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography

Mark C. Pierce; Adam Klein; James A. Burns; Milen Shishkov; B. Hyle Park; Guillermo J. Tearney; Brett E. Bouma; Steven M. Zeitels; Johannes F. De Boer

doi:10.1117/12.589870

Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography

Mark C. Pierce^*, Adam Klein, James A. Burns, Milen Shishkov, B. Hyle Park, Guillermo J. Tearney, Brett E. Bouma, Steven M. Zeitels, Johannes F. De Boer

^*Corresponding author for this work

Otolaryngology

Research output: Contribution to journal › Conference article › peer-review

Abstract

Endoscopie polarization-sensitive optical coherence tomography (PS-OCT) was used to obtain cross-sectional images of laryngeal tissues in human subjects, in vivo. Imaging in tissue to a depth of 1.2 mm and with axial resolution below 10 μm enabled the epithelial layer to be readily identified in OCT intensity images, with the underlying superficial lamina propria characterized by an increased backscatter signal, and increased birefringence in polarization-sensitive images.

Original language	English (US)
Article number	69
Pages (from-to)	307-309
Number of pages	3
Journal	Progress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume	5686
DOIs	https://doi.org/10.1117/12.589870
State	Published - 2005
Event	Photonic Therapeutics and Diagnostics - San Jose, CA, United States Duration: Jan 22 2005 → Jan 25 2005

Keywords

Birefringence
Cartilage
Fiber-optic probes
Optical imaging
Otolaryngology

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Biomaterials
Atomic and Molecular Physics, and Optics
Radiology Nuclear Medicine and imaging

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10.1117/12.589870

Cite this

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title = "Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography",

abstract = "Endoscopie polarization-sensitive optical coherence tomography (PS-OCT) was used to obtain cross-sectional images of laryngeal tissues in human subjects, in vivo. Imaging in tissue to a depth of 1.2 mm and with axial resolution below 10 μm enabled the epithelial layer to be readily identified in OCT intensity images, with the underlying superficial lamina propria characterized by an increased backscatter signal, and increased birefringence in polarization-sensitive images.",

keywords = "Birefringence, Cartilage, Fiber-optic probes, Optical imaging, Otolaryngology",

author = "Pierce, {Mark C.} and Adam Klein and Burns, {James A.} and Milen Shishkov and Park, {B. Hyle} and Tearney, {Guillermo J.} and Bouma, {Brett E.} and Zeitels, {Steven M.} and {De Boer}, {Johannes F.}",

year = "2005",

doi = "10.1117/12.589870",

language = "English (US)",

volume = "5686",

pages = "307--309",

journal = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",

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note = "Photonic Therapeutics and Diagnostics ; Conference date: 22-01-2005 Through 25-01-2005",

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TY - JOUR

T1 - Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography

AU - Pierce, Mark C.

AU - Klein, Adam

AU - Burns, James A.

AU - Shishkov, Milen

AU - Park, B. Hyle

AU - Tearney, Guillermo J.

AU - Bouma, Brett E.

AU - Zeitels, Steven M.

AU - De Boer, Johannes F.

PY - 2005

Y1 - 2005

N2 - Endoscopie polarization-sensitive optical coherence tomography (PS-OCT) was used to obtain cross-sectional images of laryngeal tissues in human subjects, in vivo. Imaging in tissue to a depth of 1.2 mm and with axial resolution below 10 μm enabled the epithelial layer to be readily identified in OCT intensity images, with the underlying superficial lamina propria characterized by an increased backscatter signal, and increased birefringence in polarization-sensitive images.

AB - Endoscopie polarization-sensitive optical coherence tomography (PS-OCT) was used to obtain cross-sectional images of laryngeal tissues in human subjects, in vivo. Imaging in tissue to a depth of 1.2 mm and with axial resolution below 10 μm enabled the epithelial layer to be readily identified in OCT intensity images, with the underlying superficial lamina propria characterized by an increased backscatter signal, and increased birefringence in polarization-sensitive images.

KW - Birefringence

KW - Cartilage

KW - Fiber-optic probes

KW - Optical imaging

KW - Otolaryngology

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DO - 10.1117/12.589870

M3 - Conference article

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SN - 1605-7422

VL - 5686

SP - 307

EP - 309

JO - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

JF - Progress in Biomedical Optics and Imaging - Proceedings of SPIE

M1 - 69

T2 - Photonic Therapeutics and Diagnostics

Y2 - 22 January 2005 through 25 January 2005

ER -

Endoscopic imaging of the human vocal cords using polarization-sensitive optical coherence tomography

Abstract

Keywords

ASJC Scopus subject areas

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