The effects of prior training were determined on muscle subjected to exercised-induced injury. Rabbit tibialis anterior (TA) and extensor digitorum longus (EDL) muscles were endurance-trained with low-frequency chronic stimulation for 30 minutes/day for 15 days. Cyclic eccentric contractions (EC) were then imposed on the muscle to induce damage. Three days following exercised-induced damage, contractile properties of the TA and EDL were determined. The data demonstrated a significant treatment effect in that TA and EDL oxidative capacity and endurance increased significantly. However, this increase in oxidative capacity did not reduce the effect of damage following EC-induced exercise. The maximum tetanic tension for control TA (1726 ± 172g) was significantly greater than trained TA (1018 ± 63g) (p<0.05). however, no significant difference existed between the EDL maximum tetanic tension (p>0. 6) for the control (2305 ± 272g) and trained (2120 ± 265g) groups. This suggests that oxidative capacity is not the sole preventer of skeletal muscle damage following eccentric damage.