Enhanced magnetic resonance contrast of Fe 3O 4 nanoparticles trapped in a porous silicon nanoparticle host

Joseph M. Kinsella, Shalini Ananda, Jennifer S. Andrew, Joel F. Grondek, Miao Ping Chien, Miriam Scadeng, Nathan C. Gianneschi, Erkki Ruoslahti, Michael J. Sailor*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

Abstract

A composite material consisting of Fe 3O 4 nanoparticles embedded in a 200 nm-diameter porous Si (pSi) nanoparticle "superstructure" is prepared as a potential magnetic resonance imaging contrast agent. Dipolar magnetic coupling between Fe 3O 4 nanoparticles is enhanced due to their proximity in the pSi host matrix, resulting in an increase in the saturation magnetization and coercivity of the composite.

Original languageEnglish (US)
Pages (from-to)H248-H253
JournalAdvanced Materials
Volume23
Issue number36
DOIs
StatePublished - Sep 22 2011

Keywords

  • cancer
  • magnetic resonance imaging
  • nanomedicine
  • porous silicon
  • superparamagnetic iron oxide nanoparticles

ASJC Scopus subject areas

  • Materials Science(all)
  • Mechanics of Materials
  • Mechanical Engineering

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