Enhanced magnetic resonance contrast of Fe 3O 4 nanoparticles trapped in a porous silicon nanoparticle host

Joseph M. Kinsella; Shalini Ananda; Jennifer S. Andrew; Joel F. Grondek; Miao Ping Chien; Miriam Scadeng; Nathan C. Gianneschi; Erkki Ruoslahti; Michael J. Sailor

doi:10.1002/adma.201101877

Enhanced magnetic resonance contrast of Fe ₃O ₄ nanoparticles trapped in a porous silicon nanoparticle host

Joseph M. Kinsella, Shalini Ananda, Jennifer S. Andrew, Joel F. Grondek, Miao Ping Chien, Miriam Scadeng, Nathan C. Gianneschi, Erkki Ruoslahti, Michael J. Sailor^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

61 Scopus citations

Abstract

A composite material consisting of Fe ₃O ₄ nanoparticles embedded in a 200 nm-diameter porous Si (pSi) nanoparticle "superstructure" is prepared as a potential magnetic resonance imaging contrast agent. Dipolar magnetic coupling between Fe ₃O ₄ nanoparticles is enhanced due to their proximity in the pSi host matrix, resulting in an increase in the saturation magnetization and coercivity of the composite.

Original language	English (US)
Pages (from-to)	H248-H253
Journal	Advanced Materials
Volume	23
Issue number	36
DOIs	https://doi.org/10.1002/adma.201101877
State	Published - Sep 22 2011

Keywords

cancer
magnetic resonance imaging
nanomedicine
porous silicon
superparamagnetic iron oxide nanoparticles

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/adma.201101877

Cite this

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abstract = "A composite material consisting of Fe 3O 4 nanoparticles embedded in a 200 nm-diameter porous Si (pSi) nanoparticle {"}superstructure{"} is prepared as a potential magnetic resonance imaging contrast agent. Dipolar magnetic coupling between Fe 3O 4 nanoparticles is enhanced due to their proximity in the pSi host matrix, resulting in an increase in the saturation magnetization and coercivity of the composite.",

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AU - Kinsella, Joseph M.

AU - Ananda, Shalini

AU - Andrew, Jennifer S.

AU - Grondek, Joel F.

AU - Chien, Miao Ping

AU - Scadeng, Miriam

AU - Gianneschi, Nathan C.

AU - Ruoslahti, Erkki

AU - Sailor, Michael J.

PY - 2011/9/22

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AB - A composite material consisting of Fe 3O 4 nanoparticles embedded in a 200 nm-diameter porous Si (pSi) nanoparticle "superstructure" is prepared as a potential magnetic resonance imaging contrast agent. Dipolar magnetic coupling between Fe 3O 4 nanoparticles is enhanced due to their proximity in the pSi host matrix, resulting in an increase in the saturation magnetization and coercivity of the composite.

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KW - magnetic resonance imaging

KW - nanomedicine

KW - porous silicon

KW - superparamagnetic iron oxide nanoparticles

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