Environmental and genetic risk factors for gastric cancer

Dhavan Shah, David Bentrem*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


Gastric cancer is a heterogeneous and prevalent disease. The traditional environmental exposures associated with an elevated risk of gastric cancer are less prevalent in the United States today. Genetic risks and risks associated with inflammation remain. Most cases are sporadic and familial clustering is observed in about 10% of the cases. Hereditary gastric cancer accounts for a very low percentage of cases. Here we review the genetic and environmental risk factors associated with the disease.

Original languageEnglish (US)
Pages (from-to)1096-1103
Number of pages8
JournalJournal of surgical oncology
Issue number7
StatePublished - Jun 2022


  • H. pylori
  • adenocarcinoma
  • diet
  • stomach

ASJC Scopus subject areas

  • Surgery
  • Oncology


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