Enzyme encapsulation in metal-organic frameworks for applications in catalysis

Marek B. Majewski, Ashlee J. Howarth, Peng Li, Michael R. Wasielewski, Joseph T. Hupp, Omar K. Farha*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

246 Scopus citations


Enzymes are natural catalysts which are highly selective and efficient. Given that enzymes have very intricate and delicate structures, they need to be stabilized and protected by a support material if they are to be used under challenging catalytic conditions. This highlight focuses on the use of metal-organic frameworks as supports for enzyme encapsulation and subsequent catalytic applications. De novo and post-synthetic methods of encapsulation are discussed and the relative catalytic activities of the enzyme@MOF composites versus free enzymes are highlighted.

Original languageEnglish (US)
Pages (from-to)4082-4091
Number of pages10
Issue number29
StatePublished - 2017

ASJC Scopus subject areas

  • General Chemistry
  • General Materials Science
  • Condensed Matter Physics


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