Enzyme mimics based upon supramolecular coordination chemistry

Michael J. Wiester, Pirmin A. Ulmann, Chad A. Mirkin

Research output: Contribution to journalReview articlepeer-review

536 Scopus citations

Abstract

Not just copies: Recent advances in supramolecular coordination chemistry have allowed chemists to synthesize macromolecular complexes that exhibit various properties intrinsic to enzymes. This Review focuses on structures inspired by properties and functions observed in enzymes rather than precise models of enzyme active sites. Many of the structures exhibit reactivity and specificity reminiscent of natural systems, and some of them have functions that exceed the natural systems which provided the inspiration for initially making them.

Original languageEnglish (US)
Pages (from-to)114-137
Number of pages24
JournalAngewandte Chemie - International Edition
Volume50
Issue number1
DOIs
StatePublished - Jan 3 2011

Keywords

  • coordination chemistry
  • enzyme mimics
  • host-guest systems
  • self-assembly
  • supramolecular chemistry

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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