Enzyme mimics based upon supramolecular coordination chemistry

Michael J. Wiester; Pirmin A. Ulmann; Chad A. Mirkin

doi:10.1002/anie.201000380

Enzyme mimics based upon supramolecular coordination chemistry

Michael J. Wiester, Pirmin A. Ulmann, Chad A. Mirkin

Chemistry

Research output: Contribution to journal › Review article › peer-review

536 Scopus citations

Abstract

Not just copies: Recent advances in supramolecular coordination chemistry have allowed chemists to synthesize macromolecular complexes that exhibit various properties intrinsic to enzymes. This Review focuses on structures inspired by properties and functions observed in enzymes rather than precise models of enzyme active sites. Many of the structures exhibit reactivity and specificity reminiscent of natural systems, and some of them have functions that exceed the natural systems which provided the inspiration for initially making them.

Original language	English (US)
Pages (from-to)	114-137
Number of pages	24
Journal	Angewandte Chemie - International Edition
Volume	50
Issue number	1
DOIs	https://doi.org/10.1002/anie.201000380
State	Published - Jan 3 2011

Keywords

coordination chemistry
enzyme mimics
host-guest systems
self-assembly
supramolecular chemistry

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.201000380

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AU - Mirkin, Chad A.

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N2 - Not just copies: Recent advances in supramolecular coordination chemistry have allowed chemists to synthesize macromolecular complexes that exhibit various properties intrinsic to enzymes. This Review focuses on structures inspired by properties and functions observed in enzymes rather than precise models of enzyme active sites. Many of the structures exhibit reactivity and specificity reminiscent of natural systems, and some of them have functions that exceed the natural systems which provided the inspiration for initially making them.

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KW - host-guest systems

KW - self-assembly

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Enzyme mimics based upon supramolecular coordination chemistry

Abstract

Keywords

ASJC Scopus subject areas

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