Epedimic and endemic HLA-B and DR associations in mucocutaneous lymph node syndrome

Alan M. Krensky*, Stafford Grady, Karen M. Shanley, William Berenberg, Edmond J. Yunis

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

HLA-A,B and DR antigens were evaluated in 51 patients with mucocutaneous lymph node syndrome (Kawasaki disease) during both endemic and epidemic periods in the Boston area. Although 80% of patients were HLA-B5 (70% HLA-Bw51) during endemic periods, there were no HLA-B5 individuals during the epidemic period. There was, however, an increased incidence of HLA-Bw44 during the Boston epidemic. Such different associations in endemic versus epidemic periods suggest possible different, as yet unknown, inciting agents.

Original languageEnglish (US)
Pages (from-to)75-77
Number of pages3
JournalHuman Immunology
Volume6
Issue number2
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Fingerprint

Dive into the research topics of 'Epedimic and endemic HLA-B and DR associations in mucocutaneous lymph node syndrome'. Together they form a unique fingerprint.

Cite this