Epidemiology and diagnosis of health care - Associated infections in the NICU

Richard A. Polin*, Susan Denson, Michael T. Brady, Lu Ann Papile, Jill E. Baley, Waldemar A. Carlo, James J. Cummings, Praveen Kumar, Rosemarie C. Tan, Kristi L. Watterberg, Wanda D. Barfield, Ann L. Jefferies, George A. Macones, Rosalie O. Mainous, Tonse N.K. Raju, Kasper S. Wang, Jim Couto, Carrie L. Byington, H. Dele Davies, Kathryn M. EdwardsMary P. Glode, Mary Anne Jackson, Harry L. Keyserling, Yvonne A. Maldonado, Dennis L. Murray, Walter A. Orenstein, Gordon E. Schutze, Rodney E. Willoughby, Theoklis E. Zaoutis, Marc A. Fischer, Bruce Gellin, Richard L. Gorman, Lucia Lee, R. Douglas Pratt, Jennifer S. Read, Joan Robinson, Marco Aurelio Palazzi Safadi, Jane Seward, Jeffrey R. Starke, Geoffrey Simon, Tina Q. Tan, Carol J. Baker, Henry H. Bernstein, David W. Kimberlin, Sarah S. Long, H. Cody Meissner, Larry K. Pickering, Lorry G. Rubin, Jennifer Frantz

*Corresponding author for this work

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

Health care-associated infections in the NICU are a major clinical problem resulting in increased morbidity and mortality, prolonged length of hospital stays, and increased medical costs. Neonates are at high risk for health care-associated infections because of impaired host defense mechanisms, limited amounts of protective endogenous flora on skin and mucosal surfaces at time of birth, reduced barrier function of neonatal skin, the use of invasive procedures and devices, and frequent exposure to broad-spectrum antibiotics. This statement will review the epidemiology and diagnosis of health care-associated infections in newborn infants.

Original languageEnglish (US)
Pages (from-to)e1104-e1109
JournalPediatrics
Volume129
Issue number4
DOIs
StatePublished - Apr 2012

Keywords

  • Antibiotics
  • Health care-associated infection
  • NICU
  • Neonate
  • Newborn
  • Nosocomial infection

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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    Polin, R. A., Denson, S., Brady, M. T., Papile, L. A., Baley, J. E., Carlo, W. A., Cummings, J. J., Kumar, P., Tan, R. C., Watterberg, K. L., Barfield, W. D., Jefferies, A. L., Macones, G. A., Mainous, R. O., Raju, T. N. K., Wang, K. S., Couto, J., Byington, C. L., Davies, H. D., ... Frantz, J. (2012). Epidemiology and diagnosis of health care - Associated infections in the NICU. Pediatrics, 129(4), e1104-e1109. https://doi.org/10.1542/peds.2012-0147