Abstract
Monitoring the composition, blood flow properties, and hydration status of human skin can be important in diagnosing disease and tracking overall health. Current methods are largely limited to clinical environments, and they primarily measure properties of superficial layers of the skin, such as the stratum corneum (10–40 µm). This work introduces soft, skin-like thermal depth sensors (e-TDS) in designs that seamlessly couple with human skin and measure its thermal properties with depth sensitivity that can extend up to 6 mm beneath the surface. Guidelines for tailoring devices to enable measurements through different effective depths follow from a systematic set of experiments, supported by theoretical modeling. On-body testing validates the physiological relevance of measurements using the e-TDS platform, with potential to aid the diagnosis of deep cutaneous and systemic diseases. Specific demonstrations include measurements that capture responses ranging from superficial changes in skin properties that result from application of a moisturizer, to changes in microvascular flow at intermediate depths induced by heating/cooling, to detection of inflammation in the deep dermis and subcutaneous fat in an incidence of a local bacterial infection, cellulitis.
| Original language | English (US) |
|---|---|
| Article number | 1802083 |
| Journal | Advanced Functional Materials |
| Volume | 28 |
| Issue number | 34 |
| DOIs | |
| State | Published - Aug 22 2018 |
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Keywords
- depth sensing
- epidermal electronics
- monitoring skin health
- thermal conductivity
- thermal sensors
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Chemistry(all)
- Materials Science(all)
- Condensed Matter Physics
- Electrochemistry
Cite this
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Epidermal Electronic Systems for Measuring the Thermal Properties of Human Skin at Depths of up to Several Millimeters. / Madhvapathy, Surabhi R.; Ma, Yinji; Patel, Manish; Krishnan, Siddharth; Wei, Chen; Li, Yajing; Xu, Shuai; Feng, Xue; Huang, Yonggang; Rogers, John A.
In: Advanced Functional Materials, Vol. 28, No. 34, 1802083, 22.08.2018.Research output: Contribution to journal › Article
TY - JOUR
T1 - Epidermal Electronic Systems for Measuring the Thermal Properties of Human Skin at Depths of up to Several Millimeters
AU - Madhvapathy, Surabhi R.
AU - Ma, Yinji
AU - Patel, Manish
AU - Krishnan, Siddharth
AU - Wei, Chen
AU - Li, Yajing
AU - Xu, Shuai
AU - Feng, Xue
AU - Huang, Yonggang
AU - Rogers, John A
PY - 2018/8/22
Y1 - 2018/8/22
N2 - Monitoring the composition, blood flow properties, and hydration status of human skin can be important in diagnosing disease and tracking overall health. Current methods are largely limited to clinical environments, and they primarily measure properties of superficial layers of the skin, such as the stratum corneum (10–40 µm). This work introduces soft, skin-like thermal depth sensors (e-TDS) in designs that seamlessly couple with human skin and measure its thermal properties with depth sensitivity that can extend up to 6 mm beneath the surface. Guidelines for tailoring devices to enable measurements through different effective depths follow from a systematic set of experiments, supported by theoretical modeling. On-body testing validates the physiological relevance of measurements using the e-TDS platform, with potential to aid the diagnosis of deep cutaneous and systemic diseases. Specific demonstrations include measurements that capture responses ranging from superficial changes in skin properties that result from application of a moisturizer, to changes in microvascular flow at intermediate depths induced by heating/cooling, to detection of inflammation in the deep dermis and subcutaneous fat in an incidence of a local bacterial infection, cellulitis.
AB - Monitoring the composition, blood flow properties, and hydration status of human skin can be important in diagnosing disease and tracking overall health. Current methods are largely limited to clinical environments, and they primarily measure properties of superficial layers of the skin, such as the stratum corneum (10–40 µm). This work introduces soft, skin-like thermal depth sensors (e-TDS) in designs that seamlessly couple with human skin and measure its thermal properties with depth sensitivity that can extend up to 6 mm beneath the surface. Guidelines for tailoring devices to enable measurements through different effective depths follow from a systematic set of experiments, supported by theoretical modeling. On-body testing validates the physiological relevance of measurements using the e-TDS platform, with potential to aid the diagnosis of deep cutaneous and systemic diseases. Specific demonstrations include measurements that capture responses ranging from superficial changes in skin properties that result from application of a moisturizer, to changes in microvascular flow at intermediate depths induced by heating/cooling, to detection of inflammation in the deep dermis and subcutaneous fat in an incidence of a local bacterial infection, cellulitis.
KW - depth sensing
KW - epidermal electronics
KW - monitoring skin health
KW - thermal conductivity
KW - thermal sensors
UR - http://www.scopus.com/inward/record.url?scp=85051770654&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85051770654&partnerID=8YFLogxK
U2 - 10.1002/adfm.201802083
DO - 10.1002/adfm.201802083
M3 - Article
VL - 28
JO - Advanced Functional Materials
JF - Advanced Functional Materials
SN - 1616-301X
IS - 34
M1 - 1802083
ER -