Abstract
Background: ABC importers utilize the energy of ATP hydrolysis to transport substrates into the cell. Results: EPR studies show how three transmembrane gates of MolB2C2-A work in concert to allow substrate to enter the cytoplasm. Conclusion: The movements of these gates indicate an opening and closing limited to small substrates. Significance: This model sheds light on how small nutrients are transported across the membrane.
Original language | English (US) |
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Pages (from-to) | 21228-21235 |
Number of pages | 8 |
Journal | Journal of Biological Chemistry |
Volume | 288 |
Issue number | 29 |
DOIs | |
State | Published - Jul 19 2013 |
ASJC Scopus subject areas
- Molecular Biology
- Biochemistry
- Cell Biology