ERCP in potentially resectable malignant biliary obstruction is frequently unsuccessful when performed outside of a comprehensive pancreaticobiliary center

Erica Donnan, David J. Bentrem, Srinadh Komanduri, David M. Mahvi, Rajesh N. Keswani*

*Corresponding author for this work

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

Background and Objectives ERCP prior to pancreaticoduodenectomy is unnecessary in select patients. When performed, it should be in conjunction with endoscopic ultrasound (EUS) to increase diagnostic sensitivity and allow for metal stent placement. The aim of this study was to determine differences in endoscopic practice patterns at community medical centers (CMC) and a comprehensive pancreaticobiliary referral center (PBRC). Methods Retrospective cohort study of all patients seen at a PBRC for endoscopic and/or surgical management of potentially resectable malignant distal biliary obstruction from 1/2011 to 6/2014. Results Of 75 patients, 30 underwent endoscopic management at a CMC and 45 were initially managed at our PBRC. ERCP was attempted in 92% of patients. EUS was performed more frequently (100% vs. 13.3 %, P < 0.0001), ERCP was more successful (93% vs. 69%, P = 0.02), and metal stent placement more likely (41% vs. 5%, P = 0.005) at our PBRC compared to a CMC. The majority (81%) of patients undergoing initial endoscopy at a CMC required repeat endoscopy at our PBRC. Conclusions Patients who are candidates for pancreaticoduodenectomy frequently undergo ERCP. At a CMC, ERCP is often unsuccessful, is rarely accompanied by EUS, and often requires repeat endoscopy. Our findings support regionalizing the management of suspected pancreatic malignancy into dedicated specialty centers. J. Surg. Oncol. 2016;113:647-651.

Original languageEnglish (US)
Pages (from-to)647-651
Number of pages5
JournalJournal of surgical oncology
Volume113
Issue number6
DOIs
StatePublished - May 1 2016

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Keywords

  • cholangiopancreatography, endoscopic retrograde
  • endoscopic ultrasound-guided fine needle aspiration
  • pancreatic neoplasm

ASJC Scopus subject areas

  • Surgery
  • Oncology

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