Erratum: Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine (Molecular Cell (2022) 82(15) (2797–2814.e11), (S109727652200483X), (10.1016/j.molcel.2022.05.016))

Daniel Arango, David Sturgill, Renbin Yang, Tapan Kanai, Paulina Bauer, Jyoti Roy, Ziqiu Wang, Masaki Hosogane, Sarah Schiffers, Shalini Oberdoerffer

Research output: Contribution to journalComment/debatepeer-review

Abstract

(Molecular Cell 82, 2797–2814.e1–e11; August 4, 2022) The authors have reported a modeling discrepancy for the cryo-EM complexes shown in Figures 7E and 7F. Automatic real-space refinement during PDB submission identified a range of 2.1–2.7 Å for the intermolecular hydrogen bond detected in the non-acetylated complex. References to the distance between the ribose 2′-OH and t6A carboxyl side chain in 80S initiation complexes formed on non-acetylated mRNA, depicted in Figure 7F, have been modified from “2.1 Å” to “2.1 or 2.7 Å after real-space refinement” to reflect this ambiguity in program-specific parameters. Corresponding labels in the graphical abstract and Figure 7F have also been updated to reflect this new information. The acetylated complex was unaltered and the range does not change the conclusion of the study.[Formula

Original languageEnglish (US)
Pages (from-to)2912
Number of pages1
JournalMolecular cell
Volume82
Issue number15
DOIs
StatePublished - Aug 4 2022

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

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