'Eruptive syringoma': A misnomer for a reactive eccrine gland ductal proliferation?

Joan Guitart*, M. M. Rosenbaum, L. Requena

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

72 Scopus citations


Background: Syringomas have traditionally been categorized as benign neoplasms of the eccrine gland ductal epithelium. However, the variety of clinical presentations reported in the literature and some cases recently observed by the authors cast doubt upon the neoplastic nature of eruptive syringomas. Our goal is to challenge the traditional notion that eruptive syringomas are neoplastic lesions. Results: We observed two patients who presented with an eczematous process, which resolved leaving residual lesions. Biopsies of the late lesions showed features of eccrine syringoma. Yet a biopsy obtained from an incipient lesion in one of the cases showed a lymphocytic inflammatory reaction of the superficial portion of the eccrine duct resulting in tortuous hyperplastic changes. Conclusion: Based on our observations, some of the so-called 'eruptive syringoma' may represent a hyperplastic response of the eccrine duct to an inflammatory reaction rather than a true adnexal neoplasm. We proposed the term 'syringomatous dermatitis' for such cases.

Original languageEnglish (US)
Pages (from-to)202-205
Number of pages4
JournalJournal of cutaneous pathology
Issue number3
StatePublished - Mar 2003

ASJC Scopus subject areas

  • Dermatology
  • Pathology and Forensic Medicine
  • Histology


Dive into the research topics of ''Eruptive syringoma': A misnomer for a reactive eccrine gland ductal proliferation?'. Together they form a unique fingerprint.

Cite this