Esophageal impedance monitoring for gastroesophageal reflux

Hayat M. Mousa, Rachel Rosen, Frederick W. Woodley, Marina Orsi, Daneila Armas, Christophe Faure, John Fortunato, Judith O'Connor, Beth Skaggs, Samuel Nurko

Research output: Contribution to journalReview articlepeer-review

94 Scopus citations


Dual pH-multichannel intraluminal impedance (pH-MII) is a sensitive tool for evaluating overall gastroesophageal reflux disease, and particularly for permitting detection of nonacid reflux events. pH-MII technology is especially useful in the postprandial period or at other times when gastric contents are nonacidic.pH-MII was recently recognized by the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition as being superior to pH monitoring alone for evaluation of the temporal relation between symptoms and gastroesophageal reflux. In children, pH-MII is useful to correlate symptoms with reflux (particularly nonacid reflux), to quantify reflux during tube feedings and the postprandial period, and to assess efficacy of antireflux therapy. This clinical review is simply an evidence-based overview addressing the indications, limitations, and recommended protocol for the clinical use of pH-MII in children.

Original languageEnglish (US)
Pages (from-to)129-139
Number of pages11
JournalJournal of pediatric gastroenterology and nutrition
Issue number2
StatePublished - Feb 2011


  • acid gastroesophageal reflux
  • bolus contact time
  • gastroesophageal reflux
  • gastroesophageal reflux disease
  • multichannel intraluminal impedance
  • nonacid gastroesophageal reflux

ASJC Scopus subject areas

  • Gastroenterology
  • Pediatrics, Perinatology, and Child Health


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