TY - JOUR
T1 - Esophagogastric Junction Opening Parameters Are Consistently Abnormal in Untreated Achalasia
AU - Rooney, Katharine P.
AU - Baumann, Alexandra J.
AU - Donnan, Erica
AU - Kou, Wenjun
AU - Triggs, Joseph R.
AU - Prescott, Jacqueline
AU - Decorrevont, Alex
AU - Dorian, Emily
AU - Kahrilas, Peter J.
AU - Pandolfino, John E.
AU - Carlson, Dustin A.
N1 - Funding Information:
Conflicts of interest These authors disclose the following: Dustin A. Carlson, Peter J. Kahrilas, and John E. Pandolfino hold shared intellectual property rights and ownership surrounding FLIP panometry systems, methods, and apparatus with Medtronic Inc. Dustin A. Carlson has served as a speaker and consultant for Medtronic. Wenjun Kou has served as a consultant for Crospon, Inc. Peter J. Kahrilas has served as a consultant for Ironwood. John E. Pandolfino owns stock options in Crospon, Inc (stock options); has served as a consultant for Given Imaging, Sandhill Scientific, Medtronic, Torax, and Ironwood; has received grant support from Given Imaging and Impleo; and has served as a speaker for Given Imaging, Sandhill Scientific, Takeda, AstraZeneca, Medtronic, Torax, Ironwood, and Impleo. The remaining authors disclose no conflicts.
PY - 2021/5
Y1 - 2021/5
N2 - Achalasia is a disorder of impaired lower esophageal sphincter (LES) relaxation and failed peristalsis traditionally characterized by manometry.1 As impaired LES relaxation is a mechanism of reduced esophagogastric junction (EGJ) opening, abnormally reduced EGJ distensibility assessed with functional luminal imaging probe (FLIP) was reported among patients with untreated achalasia.2–5 Therefore, we aimed to describe the performance characteristics of EGJ opening parameters on FLIP panometry among a large cohort of treatment-naïve achalasia patients.
AB - Achalasia is a disorder of impaired lower esophageal sphincter (LES) relaxation and failed peristalsis traditionally characterized by manometry.1 As impaired LES relaxation is a mechanism of reduced esophagogastric junction (EGJ) opening, abnormally reduced EGJ distensibility assessed with functional luminal imaging probe (FLIP) was reported among patients with untreated achalasia.2–5 Therefore, we aimed to describe the performance characteristics of EGJ opening parameters on FLIP panometry among a large cohort of treatment-naïve achalasia patients.
UR - http://www.scopus.com/inward/record.url?scp=85087985743&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85087985743&partnerID=8YFLogxK
U2 - 10.1016/j.cgh.2020.03.069
DO - 10.1016/j.cgh.2020.03.069
M3 - Short survey
C2 - 32289545
AN - SCOPUS:85087985743
SN - 1542-3565
VL - 19
SP - 1058-1060.e1
JO - Clinical Gastroenterology and Hepatology
JF - Clinical Gastroenterology and Hepatology
IS - 5
ER -