Estimates of body fat in children by hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution

Delphine R. Robotham; Dale A. Schoeller; Arlene B. Mercado; Margaret C. Mirch; Kelly R. Theim; James C. Reynolds; Jack A. Yanovski

doi:10.1097/01.mpg.0000189373.31697.15

Estimates of body fat in children by hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution

Delphine R. Robotham, Dale A. Schoeller, Arlene B. Mercado, Margaret C. Mirch, Kelly R. Theim, James C. Reynolds, Jack A. Yanovski^*

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

We evaluated the accuracy with which the Hologic QDR-4500A and QDR-2000 densitometers measure fat mass (FM) in 95 children. FM was derived from total body water measured by deuterium dilution (DD) in all children, by QDR-4500A in 50, and by QDR-2000 in 45 children. Compared with DD, both instruments underestimated FM (QDR-4500A: 3.35 ± 2.5 kg, P < 0.0001; QDR-2000: 1.05 ± 1.5 kg, P < 0.0001). Both absorptiometers showed magnitude biases relative to DD (QDR-4500: r = +0.70, P < 0.001; QDR-2000: r = -0.51, P < 0.001). We conclude that neither densitometer is equivalent to DD for estimation of children's FM. The QDR-4500A's current calibration seems to provide an even greater underestimate of FM than the QDR-2000.

Original language	English (US)
Pages (from-to)	331-335
Number of pages	5
Journal	Journal of pediatric gastroenterology and nutrition
Volume	42
Issue number	3
DOIs	https://doi.org/10.1097/01.mpg.0000189373.31697.15
State	Published - Mar 2006

Keywords

Body composition
Calibration
Children
Dual-energy X-ray absorptiometry
Fat mass

ASJC Scopus subject areas

Gastroenterology
Pediatrics, Perinatology, and Child Health

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10.1097/01.mpg.0000189373.31697.15

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Robotham, D. R., Schoeller, D. A., Mercado, A. B., Mirch, M. C., Theim, K. R., Reynolds, J. C., & Yanovski, J. A. (2006). Estimates of body fat in children by hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution. Journal of pediatric gastroenterology and nutrition, 42(3), 331-335. https://doi.org/10.1097/01.mpg.0000189373.31697.15

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title = "Estimates of body fat in children by hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution",

abstract = "We evaluated the accuracy with which the Hologic QDR-4500A and QDR-2000 densitometers measure fat mass (FM) in 95 children. FM was derived from total body water measured by deuterium dilution (DD) in all children, by QDR-4500A in 50, and by QDR-2000 in 45 children. Compared with DD, both instruments underestimated FM (QDR-4500A: 3.35 ± 2.5 kg, P < 0.0001; QDR-2000: 1.05 ± 1.5 kg, P < 0.0001). Both absorptiometers showed magnitude biases relative to DD (QDR-4500: r = +0.70, P < 0.001; QDR-2000: r = -0.51, P < 0.001). We conclude that neither densitometer is equivalent to DD for estimation of children's FM. The QDR-4500A's current calibration seems to provide an even greater underestimate of FM than the QDR-2000.",

keywords = "Body composition, Calibration, Children, Dual-energy X-ray absorptiometry, Fat mass",

author = "Robotham, {Delphine R.} and Schoeller, {Dale A.} and Mercado, {Arlene B.} and Mirch, {Margaret C.} and Theim, {Kelly R.} and Reynolds, {James C.} and Yanovski, {Jack A.}",

year = "2006",

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doi = "10.1097/01.mpg.0000189373.31697.15",

language = "English (US)",

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T1 - Estimates of body fat in children by hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution

AU - Robotham, Delphine R.

AU - Schoeller, Dale A.

AU - Mercado, Arlene B.

AU - Mirch, Margaret C.

AU - Theim, Kelly R.

AU - Reynolds, James C.

AU - Yanovski, Jack A.

PY - 2006/3

Y1 - 2006/3

N2 - We evaluated the accuracy with which the Hologic QDR-4500A and QDR-2000 densitometers measure fat mass (FM) in 95 children. FM was derived from total body water measured by deuterium dilution (DD) in all children, by QDR-4500A in 50, and by QDR-2000 in 45 children. Compared with DD, both instruments underestimated FM (QDR-4500A: 3.35 ± 2.5 kg, P < 0.0001; QDR-2000: 1.05 ± 1.5 kg, P < 0.0001). Both absorptiometers showed magnitude biases relative to DD (QDR-4500: r = +0.70, P < 0.001; QDR-2000: r = -0.51, P < 0.001). We conclude that neither densitometer is equivalent to DD for estimation of children's FM. The QDR-4500A's current calibration seems to provide an even greater underestimate of FM than the QDR-2000.

AB - We evaluated the accuracy with which the Hologic QDR-4500A and QDR-2000 densitometers measure fat mass (FM) in 95 children. FM was derived from total body water measured by deuterium dilution (DD) in all children, by QDR-4500A in 50, and by QDR-2000 in 45 children. Compared with DD, both instruments underestimated FM (QDR-4500A: 3.35 ± 2.5 kg, P < 0.0001; QDR-2000: 1.05 ± 1.5 kg, P < 0.0001). Both absorptiometers showed magnitude biases relative to DD (QDR-4500: r = +0.70, P < 0.001; QDR-2000: r = -0.51, P < 0.001). We conclude that neither densitometer is equivalent to DD for estimation of children's FM. The QDR-4500A's current calibration seems to provide an even greater underestimate of FM than the QDR-2000.

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KW - Dual-energy X-ray absorptiometry

KW - Fat mass

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Estimates of body fat in children by hologic QDR-2000 and QDR-4500A dual-energy X-ray absorptiometers compared with deuterium dilution

Abstract

Keywords

ASJC Scopus subject areas

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