Ethics of controlled human infection to address COVID-19

Seema K. Shah; Franklin G. Miller; Thomas C. Darton; Devan Duenas; Claudia Emerson; Holly Fernandez Lynch; Euzebiusz Jamrozik; Nancy S. Jecker; Dorcas Kamuya; Melissa Kapulu; Jonathan Kimmelman; Douglas MacKay; Matthew J. Memoli; Sean C. Murphy; Ricardo Palacios; Thomas L. Richie; Meta Roestenberg; Abha Saxena; Katherine Saylor; Michael J. Selgelid; Vina Vaswani; Annette Rid

doi:10.1126/science.abc1076

Ethics of controlled human infection to address COVID-19

Seema K. Shah^*, Franklin G. Miller, Thomas C. Darton, Devan Duenas, Claudia Emerson, Holly Fernandez Lynch, Euzebiusz Jamrozik, Nancy S. Jecker, Dorcas Kamuya, Melissa Kapulu, Jonathan Kimmelman, Douglas MacKay, Matthew J. Memoli, Sean C. Murphy, Ricardo Palacios, Thomas L. Richie, Meta Roestenberg, Abha Saxena, Katherine Saylor, Michael J. SelgelidVina Vaswani, Annette Rid

^*Corresponding author for this work

Pediatrics

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Original language	English (US)
Pages (from-to)	832-834
Number of pages	3
Journal	Science
Volume	368
Issue number	6493
DOIs	https://doi.org/10.1126/science.abc1076
State	Published - May 22 2020

ASJC Scopus subject areas

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Shah, S. K., Miller, F. G., Darton, T. C., Duenas, D., Emerson, C., Lynch, H. F., Jamrozik, E., Jecker, N. S., Kamuya, D., Kapulu, M., Kimmelman, J., MacKay, D., Memoli, M. J., Murphy, S. C., Palacios, R., Richie, T. L., Roestenberg, M., Saxena, A., Saylor, K., ... Rid, A. (2020). Ethics of controlled human infection to address COVID-19. Science, 368(6493), 832-834. https://doi.org/10.1126/science.abc1076

Shah, Seema K. ; Miller, Franklin G. ; Darton, Thomas C. ; Duenas, Devan ; Emerson, Claudia ; Lynch, Holly Fernandez ; Jamrozik, Euzebiusz ; Jecker, Nancy S. ; Kamuya, Dorcas ; Kapulu, Melissa ; Kimmelman, Jonathan ; MacKay, Douglas ; Memoli, Matthew J. ; Murphy, Sean C. ; Palacios, Ricardo ; Richie, Thomas L. ; Roestenberg, Meta ; Saxena, Abha ; Saylor, Katherine ; Selgelid, Michael J. ; Vaswani, Vina ; Rid, Annette. / Ethics of controlled human infection to address COVID-19. In: Science. 2020 ; Vol. 368, No. 6493. pp. 832-834.

@article{ba1f0a95f40a4b89a066ceea56fd26bc,

title = "Ethics of controlled human infection to address COVID-19",

author = "Shah, {Seema K.} and Miller, {Franklin G.} and Darton, {Thomas C.} and Devan Duenas and Claudia Emerson and Lynch, {Holly Fernandez} and Euzebiusz Jamrozik and Jecker, {Nancy S.} and Dorcas Kamuya and Melissa Kapulu and Jonathan Kimmelman and Douglas MacKay and Memoli, {Matthew J.} and Murphy, {Sean C.} and Ricardo Palacios and Richie, {Thomas L.} and Meta Roestenberg and Abha Saxena and Katherine Saylor and Selgelid, {Michael J.} and Vina Vaswani and Annette Rid",

note = "Funding Information: The opinions expressed in the article are the authors? and do not reflect the views of organizations with which the authors have affiliations, including the National Institutes of Health, the Department of Health and Human Services, or the United States government. This work was primarily supported by a Making a Difference Grant from the Greenwall Foundation (S.K.S., A.R., R.P., D.D.), along with support from the Wellcome Trust (S.K.S., E.J., D.K., M.K., R.P., M.J.S., V.V.), Brocher Foundation (S.K.S., A.R., R.P., D.D., T.C.D., H.F.L., E.J., N.S.J., D.K., J.K., D.M., S.C.M., T.L.R., M.R., A.S., M.J.S., V.V.), and NIH Clinical Center Department of Bioethics (A.R.). The authors also thank C. Chui, K. Littler, P. Pitisuttithum, and M. Yu for their contributions, and M. Danis, C. Grady, M. Nicolini, J. Ochoa, and H. Taylor for helpful discussion.",

year = "2020",

month = may,

day = "22",

doi = "10.1126/science.abc1076",

language = "English (US)",

volume = "368",

pages = "832--834",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "6493",

}

Shah, SK, Miller, FG, Darton, TC, Duenas, D, Emerson, C, Lynch, HF, Jamrozik, E, Jecker, NS, Kamuya, D, Kapulu, M, Kimmelman, J, MacKay, D, Memoli, MJ, Murphy, SC, Palacios, R, Richie, TL, Roestenberg, M, Saxena, A, Saylor, K, Selgelid, MJ, Vaswani, V & Rid, A 2020, 'Ethics of controlled human infection to address COVID-19', Science, vol. 368, no. 6493, pp. 832-834. https://doi.org/10.1126/science.abc1076

Ethics of controlled human infection to address COVID-19. / Shah, Seema K.; Miller, Franklin G.; Darton, Thomas C.; Duenas, Devan; Emerson, Claudia; Lynch, Holly Fernandez; Jamrozik, Euzebiusz; Jecker, Nancy S.; Kamuya, Dorcas; Kapulu, Melissa; Kimmelman, Jonathan; MacKay, Douglas; Memoli, Matthew J.; Murphy, Sean C.; Palacios, Ricardo; Richie, Thomas L.; Roestenberg, Meta; Saxena, Abha; Saylor, Katherine; Selgelid, Michael J.; Vaswani, Vina; Rid, Annette.

In: Science, Vol. 368, No. 6493, 22.05.2020, p. 832-834.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Ethics of controlled human infection to address COVID-19

AU - Shah, Seema K.

AU - Miller, Franklin G.

AU - Darton, Thomas C.

AU - Duenas, Devan

AU - Emerson, Claudia

AU - Lynch, Holly Fernandez

AU - Jamrozik, Euzebiusz

AU - Jecker, Nancy S.

AU - Kamuya, Dorcas

AU - Kapulu, Melissa

AU - Kimmelman, Jonathan

AU - MacKay, Douglas

AU - Memoli, Matthew J.

AU - Murphy, Sean C.

AU - Palacios, Ricardo

AU - Richie, Thomas L.

AU - Roestenberg, Meta

AU - Saxena, Abha

AU - Saylor, Katherine

AU - Selgelid, Michael J.

AU - Vaswani, Vina

AU - Rid, Annette

N1 - Funding Information: The opinions expressed in the article are the authors? and do not reflect the views of organizations with which the authors have affiliations, including the National Institutes of Health, the Department of Health and Human Services, or the United States government. This work was primarily supported by a Making a Difference Grant from the Greenwall Foundation (S.K.S., A.R., R.P., D.D.), along with support from the Wellcome Trust (S.K.S., E.J., D.K., M.K., R.P., M.J.S., V.V.), Brocher Foundation (S.K.S., A.R., R.P., D.D., T.C.D., H.F.L., E.J., N.S.J., D.K., J.K., D.M., S.C.M., T.L.R., M.R., A.S., M.J.S., V.V.), and NIH Clinical Center Department of Bioethics (A.R.). The authors also thank C. Chui, K. Littler, P. Pitisuttithum, and M. Yu for their contributions, and M. Danis, C. Grady, M. Nicolini, J. Ochoa, and H. Taylor for helpful discussion.

PY - 2020/5/22

Y1 - 2020/5/22

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UR - http://www.scopus.com/inward/citedby.url?scp=85085157114&partnerID=8YFLogxK

U2 - 10.1126/science.abc1076

DO - 10.1126/science.abc1076

M3 - Article

C2 - 32381590

AN - SCOPUS:85085157114

VL - 368

SP - 832

EP - 834

JO - Science

JF - Science

SN - 0036-8075

IS - 6493

ER -

Ethics of controlled human infection to address COVID-19

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