Evaluation and Management of Hepatocellular Carcinoma

Laura M. Kulik*, Attasit Chokechanachaisakul

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

35 Scopus citations

Abstract

The burden of hepatocellular carcinoma is rising and anticipated to escalate and while the best chance for long term cure remains transplantation, however the shortage of available organs remains a limitation. Liver directed therapy can serve the role of bridge/downstaging to transplant or as palliative care. Despite an improved overall survival among patients with HCC, due to advancements in surgical techniques, liver directed and systemic therapy, the 5 year overall survival remains low at 18% high-lightening the need for novel therapies. Surveillance for HCC is key to detect disease at an early stage to increase the chances for a potentially curative option.

Original languageEnglish (US)
Pages (from-to)23-43
Number of pages21
JournalClinics in liver disease
Volume19
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • Diagnosis
  • Evaluation
  • Hepatocellular carcinoma
  • Management
  • Treatment

ASJC Scopus subject areas

  • Hepatology

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