Evaluation and Management of Primary Hyperaldosteronism

Frances T. Lee, Dina Elaraj*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

20 Scopus citations


Primary hyperaldosteronism is an important and increasingly prevalent cause of hypertension that is characterized by unregulated aldosterone excess. More than 90% of primary hyperaldosteronism cases are attributable to either idiopathic adrenal hyperplasia or aldosterone-producing adenomas. The approach to the diagnosis of primary hyperaldosteronism should be step-wise, starting with screening of at-risk populations, confirmatory testing for positively screened patients, and subtype classification in order to direct surgical or medical management. Based on current guidelines, subtype classification of primary hyperaldosteronism should be determined with both imaging and adrenal vein sampling (AVS), reserving deferment of AVS for a selective subset of patients.

Original languageEnglish (US)
Pages (from-to)731-745
Number of pages15
JournalSurgical Clinics of North America
Issue number4
StatePublished - Aug 2019


  • Adenoma
  • Adrenal hyperplasia
  • Aldosterone excess
  • Hyperaldosteronism
  • Primary hyperaldosteronism

ASJC Scopus subject areas

  • Surgery


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