Evaluation of a Text Messaging-Based Human Papillomavirus Vaccination Intervention for Young Sexual Minority Men: Results from a Pilot Randomized Controlled Trial

Mary Ann Gerend, Krystal Madkins, Shariell Crosby, Aaron K. Korpak, Gregory L. Phillips, Michael Bass, Magda Houlberg, Brian Mustanski

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Men who have sex with men (MSM) are at high risk for human papillomavirus (HPV) infection and HPV-related anal cancer. Although a safe and effective vaccine is available to prevent HPV infection, HPV vaccine uptake among young MSM remains low. PURPOSE: This pilot randomized controlled trial tested the acceptability, feasibility, and preliminary efficacy of a text messaging-based HPV vaccination intervention for young sexual minority men. METHODS: In 2018, unvaccinated sexual minority men aged 18-25 years were recruited from Chicago to participate in a 9 month sexual health program called txt2protect. Participants (N = 150) were randomized to the intervention or control condition. Intervention condition messages focused primarily on HPV vaccination, with only a brief mention of other sexual health practices (e.g., condom use and HIV testing), while control condition messages focused on a variety of sexual health practices with only a brief mention of HPV vaccination. Participants received daily text messages for the first 3 weeks and monthly text messages for the remaining ~8 months of the trial. Participants completed surveys at baseline and 3 week and 9 month follow-ups. RESULTS: Participants reported high satisfaction with the intervention. Although trial retention was high (with over 88% completing the 9 month survey), the study fell short of meeting its recruitment goal. HPV vaccine series initiation was significantly higher among intervention participants (19.4%) compared to control participants (6.6%), odds ratio = 3.43, 95% confidence interval: 1.17, 10.08. CONCLUSIONS: Findings suggest that txt2protect is an acceptable and potentially promising intervention for increasing HPV vaccine initiation among young sexual minority men. CLINICAL TRIAL REGISTRATION: NCT02994108.

Original languageEnglish (US)
Pages (from-to)321-332
Number of pages12
JournalAnnals of behavioral medicine : a publication of the Society of Behavioral Medicine
Volume55
Issue number4
DOIs
StatePublished - Apr 7 2021

Keywords

  • Cancer prevention
  • Human papillomavirus vaccination
  • Men who have sex with men
  • Mobile health (mHealth) intervention

ASJC Scopus subject areas

  • Psychology(all)
  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Evaluation of a Text Messaging-Based Human Papillomavirus Vaccination Intervention for Young Sexual Minority Men: Results from a Pilot Randomized Controlled Trial'. Together they form a unique fingerprint.

Cite this