Evaluation of an implantable MOSFET dosimeter designed for use with hypofractionated external beam treatments and its applications for breast and prostate treatments

Gloria P. Beyer*, Stephen F. Kry, Eric Espenhahn, Christine Marie Rini, Elyse Boyles, Greg Mann

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Purpose: An implantable metal-oxide semiconductor field effect transistors-based dosimeter has recently been developed for the in vivo monitoring of hypofractionated radiotherapy. This DVS-HFT dosimeter is designed for fraction sizes of 340-950 cGy and can also be used for bis in die fraction monitoring. The current work reports on the testing and evaluation of this dosimeter, including both its basic characteristics as well as its performance during simulated clinical treatment plans. Methods: The authors tested the dose rate dependence of this dosimeter (300 MUmin versus 600 MUmin), the treatment time dependence (4 min per treatment versus up to 60 min per treatment), and the dose and energy dependence (6 and 18 MV irradiations of 700-900 cGy per fraction). Additionally, they irradiated the detectors in-phantom with breast and prostate hypofractionated treatments. Results: The detectors showed no significant dose rate, treatment time, energy, or dose dependence. Furthermore, the detectors were found to perform within manufacturer tolerances for all hypofractionated treatments examined, accurately reporting the measured dose (average disagreement of -0.65%). Conclusions: These dosimeters appear well suited for in vivo monitoring of hypofractionated radiotherapy doses, and thereby, have the potential to improve patient care.

Original languageEnglish (US)
Pages (from-to)4881-4887
Number of pages7
JournalMedical Physics
Volume38
Issue number8
DOIs
StatePublished - Jan 1 2011

Keywords

  • dose monitor
  • DVS
  • hypofractionation
  • implantable dosimeter
  • in vivo dosimetry
  • MOSFET
  • radiotherapy

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

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