Evaluation of Anthralin in the Treatment of Alopecia Areata

Virginia C. Fiedler-Weiss*, Cunera M. Buys

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

105 Scopus citations


Anthralin cream 0.5% to 1.0% was used to treat 68 patients with severe alopecia areata. Therapy was relatively well tolerated, although all patients experienced pruritus and local erythema and scaling. Cosmetic response was seen in 17 (25%) of the patients, and was maintained during therapy in 12 (71%) of the 17 cosmetic responders. For the patients treated with 0.5% anthralin, the mean time to response (44 of 66 patients) was 11 weeks; the mean time to cosmetic response (13 of 66 patients) was 23 weeks. Duration of the current episode of hair loss did not correlate with cosmetic response. Compared with other currently available topical treatments, anthralin appears to be a reasonable therapeutic option for severe alopecia areata.

Original languageEnglish (US)
Pages (from-to)1491-1493
Number of pages3
JournalArchives of dermatology
Issue number11
StatePublished - Nov 1987
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology


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