Evaluation of computed tomography and radionuclide scanning in the staging of cutaneous T-cell lymphoma

S. T. Rosen, R. Gore, J. Brennan, L. I. Gordon, D. Variakojis, M. M. Rosenbaum, W. Caro, H. Roenigk

Research output: Contribution to journalArticlepeer-review

Abstract

Computed tomography (CT) of the abdomen and pelvis was performed on 30 patients with cutaneous T-cell lymphoma (CTCL) as part of their pretreatment staging evaluation. Twenty-two patients also had liver spleen radionuclide scans. Physical examination revealed limited cutaneous plaque disease in five patients, extensive plaque disease in 11 patients, cutaneous tumors in six patients, and exfoliative erythroderma in eight patients. Generalized palpable adenopathy was detected in 11 patients, localized palpable adenopathy in ten patients, and no adenopathy in nine patients. Peripheral lymph node biopsy specimens showed CTCL in seven patients and dermatopathic lymphadenitis or sinus histiocytosis in 17 patients. Two patients were at disease stage Ia, five were at stage Ib, seven were at stage IIa, two were at stage IIb, seven were at stage III, and seven were at stage IVa. The CT did not reveal intra-abdominal, retroperitoneal, or pelvic adenopathy, or hepatic or splenic abnormalities in any patient. Radionuclide scans demonstrated nonspecific abnormalities in five patients, but did not appear to reflect disease involvement. Computed tomography of the abdomen and liver-spleen radionuclide scans should not be routine staging procedures for CTCL.

Original languageEnglish (US)
Pages (from-to)884-886
Number of pages3
JournalArchives of Dermatology
Volume122
Issue number8
DOIs
StatePublished - Oct 15 1986

ASJC Scopus subject areas

  • Dermatology

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