Evaluation of hydroxylapatite graft materials in canine cervical spine fusions

Stephen D. Cook; Mary C. Reynolds; Thomas S. Whitecloud; Alan S. Routman; Amanda F. Harding; John F. Kay; Michael Jarcho

doi:10.1097/00007632-198605000-00002

Evaluation of hydroxylapatite graft materials in canine cervical spine fusions

Stephen D. Cook^*, Mary C. Reynolds, Thomas S. Whitecloud, Alan S. Routman, Amanda F. Harding, John F. Kay, Michael Jarcho

^*Corresponding author for this work

Surgery

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

The efficacy of ceramic hydroxylapatite implant materials as graft materials for cervical spine fusion was evaluated in canines. Bioresorbable and non-bioresorbable systems were evaluated at time periods ranging from 1 to 24 weeks. Implant interbody position and progression of fusion were evaluated radiographically and histologically. Implant fracture and extrusion into adjacent soft tissues occurred in nine of 23 cases. Implant fracture occurred in many of the remaining 14 cases, however, the implant materials remained within the interspace. Implant fracture occurred with both implant systems. Radiographically little evidence of fusion was observed at less than 6 weeks, however by 12 weeks evidence of fusion was noted and was confirmed histologically. No difference in fusion rate or degree of fusion was observed between the two implant systems.

Original language	English (US)
Pages (from-to)	305-309
Number of pages	5
Journal	Spine
Volume	11
Issue number	4
DOIs	https://doi.org/10.1097/00007632-198605000-00002
State	Published - May 1986

Keywords

Cervical spine
Hydroxylapatite
Interbody fusion

ASJC Scopus subject areas

Orthopedics and Sports Medicine
Clinical Neurology

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10.1097/00007632-198605000-00002

Cite this

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title = "Evaluation of hydroxylapatite graft materials in canine cervical spine fusions",

abstract = "The efficacy of ceramic hydroxylapatite implant materials as graft materials for cervical spine fusion was evaluated in canines. Bioresorbable and non-bioresorbable systems were evaluated at time periods ranging from 1 to 24 weeks. Implant interbody position and progression of fusion were evaluated radiographically and histologically. Implant fracture and extrusion into adjacent soft tissues occurred in nine of 23 cases. Implant fracture occurred in many of the remaining 14 cases, however, the implant materials remained within the interspace. Implant fracture occurred with both implant systems. Radiographically little evidence of fusion was observed at less than 6 weeks, however by 12 weeks evidence of fusion was noted and was confirmed histologically. No difference in fusion rate or degree of fusion was observed between the two implant systems.",

keywords = "Cervical spine, Hydroxylapatite, Interbody fusion",

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AU - Cook, Stephen D.

AU - Reynolds, Mary C.

AU - Whitecloud, Thomas S.

AU - Routman, Alan S.

AU - Harding, Amanda F.

AU - Kay, John F.

AU - Jarcho, Michael

PY - 1986/5

Y1 - 1986/5

N2 - The efficacy of ceramic hydroxylapatite implant materials as graft materials for cervical spine fusion was evaluated in canines. Bioresorbable and non-bioresorbable systems were evaluated at time periods ranging from 1 to 24 weeks. Implant interbody position and progression of fusion were evaluated radiographically and histologically. Implant fracture and extrusion into adjacent soft tissues occurred in nine of 23 cases. Implant fracture occurred in many of the remaining 14 cases, however, the implant materials remained within the interspace. Implant fracture occurred with both implant systems. Radiographically little evidence of fusion was observed at less than 6 weeks, however by 12 weeks evidence of fusion was noted and was confirmed histologically. No difference in fusion rate or degree of fusion was observed between the two implant systems.

AB - The efficacy of ceramic hydroxylapatite implant materials as graft materials for cervical spine fusion was evaluated in canines. Bioresorbable and non-bioresorbable systems were evaluated at time periods ranging from 1 to 24 weeks. Implant interbody position and progression of fusion were evaluated radiographically and histologically. Implant fracture and extrusion into adjacent soft tissues occurred in nine of 23 cases. Implant fracture occurred in many of the remaining 14 cases, however, the implant materials remained within the interspace. Implant fracture occurred with both implant systems. Radiographically little evidence of fusion was observed at less than 6 weeks, however by 12 weeks evidence of fusion was noted and was confirmed histologically. No difference in fusion rate or degree of fusion was observed between the two implant systems.

KW - Cervical spine

KW - Hydroxylapatite

KW - Interbody fusion

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Evaluation of hydroxylapatite graft materials in canine cervical spine fusions

Abstract

Keywords

ASJC Scopus subject areas

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