Objective The aim of this study was to compare the performance of arrhythmia-insensitive rapid (AIR) and modified Look-Locker inversion recovery (MOLLI) T1 mapping in patients with cardiomyopathies. Methods In 58 patients referred for clinical cardiac magnetic resonance imaging at 1.5 T, we compared MOLLI and AIR native and postcontrast T1 measurements. Two readers independently analyzed myocardial and blood T1 values. Agreement between techniques, interreader agreement per technique, and intrascan agreement per technique were evaluated. Results The MOLLI and AIR T1 values were strongly correlated (r2 = 0.98); however, statistically significantly different T1 values were derived (bias 80 milliseconds, pooled data, P < 0.01). Both techniques demonstrated high repeatability (MOLLI, r2 = 1.00 and coefficient of repeatability [CR] = 72 milliseconds; AIR, r2 = 0.99 and CR = 184.2 milliseconds) and produced high interreader agreement (MOLLI, r2 = 1.00 and CR = 51.7 milliseconds; AIR, r2 = 0.99 and CR = 183.5 milliseconds). Conclusions Arrhythmia-insensitive rapid and MOLLI sequences produced significantly different T1 values in a diverse patient cohort.
- T1 mapping
- arrhythmia-insensitive rapid
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging