Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG, and SMUG1 genes in familial colorectal cancer predisposition

Keyphrases

• Base Excision Repair Pathway 33%
• Cancer Cases 16%
• Coding Sequence 16%
• Colorectal Cancer 33%
• Colorectal Cancer Predisposition 100%
• Colorectal Cancer Susceptibility 33%
• Disease Susceptibility 16%
• DNA Repair Genes 16%
• Dysregulation 16%
• Familial Colorectal Cancer 100%
• Germ Cells 16%
• Germline Alterations 16%
• Germline mutation 16%
• Healthy Controls 16%
• MUTYH 16%
• NEIL1 100%
• NEIL2 100%
• Novel Missense Variant 16%
• NTHL1 100%
• Oxidative DNA Damage 16%
• Pathway Genes 16%
• Patients with Colorectal Cancer 16%
• Sequence Variants 16%
• Sequence Variation 16%
• SMUG1 100%
• Susceptibility Alleles 16%
• UNG2 16%

Biochemistry, Genetics and Molecular Biology

• Allele 25%
• Base Excision Repair 50%
• DNA Repair 25%
• Germ Cell 50%
• Germline 50%
• Germline Mutation 25%
• Missense 25%
• MUTYH 25%
• NEIL1 100%
• Tiopronin 100%