Abstract
The paper reports on a study of the effect of rough interfaces on blood material interaction. To carefully evaluate the blood compatibility of smooth and rough interfaces, in vitro and ex vivo experiments were performed with the help of a newly designed pneumatically driven, small stroke volume test ventricle. The in vitro studies were performed with anticoagulated fresh bovine blood, while the ex vivo experiments were conducted in a Pulmonary Artery to Pulmonary Artery Shunt (PAPAS) model. The ex vivo shunt proved to be a good instrument to study thrombogenesis in artificial ventricles. The reported results justify further investigation of the application of rough blood contacting surfaces to improve the blood compatibility of artificial ventricles.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 732-737 |
| Number of pages | 6 |
| Journal | ASAIO Transactions |
| Volume | 33 |
| Issue number | 3 |
| State | Published - Jul 1987 |
ASJC Scopus subject areas
- Biophysics