Evaluation of total disc arthroplasty: a canine model.

Brett A. Taylor*, Gbolahan O. Okubadejo, Alpesh A. Patel, Micael R. Talcott, Toshii Imamura, Nianbin Hu, Bryan W. Cunningham

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


The study reported here was designed to examine the biomechanical and histopathologic properties of total disc arthroplasty (TDA) using a canine model. Thirty-seven dogs were divided into 3 groups (intact spine, fusion, TDA) and sacrificed either at study commencement or at 3 months. Results showed progressive fusion from 0 to 3 months in the fusion group. The TDA group maintained motion throughout this period. No neurologic complications were noted in either group. These results establish the canine as a model for future studies of TDA.

Original languageEnglish (US)
Pages (from-to)E64-70
JournalAmerican journal of orthopedics (Belle Mead, N.J.)
Issue number4
StatePublished - Apr 2008

ASJC Scopus subject areas

  • Medicine(all)

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