Evaluation of ventricular synchrony using doppler tissue imaging and strain/strain rate in patients with heart failure receiving cardiac resynchronization therapy

Lei Lei Cheng*, Jing Ping Sun, James D. Thomas

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Purpose To assess the value of doppler tissure imaging and strain/strain rate in patients with heart failure receiving cardiac resychronization therapy. Methods A biventricular (BiV) pacemaker was implanted in 34 patients with heart failure. Two-dimensional standard and Doppler tissue echocardiography was performed during right ventricular (RV), left ventricular (LV), BiV, and no pacing in a random and blinded manner. Left ventricular ejection fraction (EF) , stroke volume (SV), systolic peak myocardial velocities, segmental myocardial systolic displacement, strain/strain rate, and regional Q-wave-to-peak systolic displacement times (Ts) were measured and the impact of different underlying disease was evaluated. Results LV and BiV pacing increased SV(P<C0. 02, for both) and LVEF (P <0. 001 for both). Segmental myocardial systolic displacement was significantly improved during LV pacing. Systolic strain rate and strain improved in the apical segment of septal and lateral walls during LV pacing. Strain rate was only improved significantly during BiV pacing in the apical segment of the lateral wall. No significant difference was found between patients with ischemia and non-ischemia. Conclusions LV and BiV pacing provide benefits for patients with heart failure. Doppler tissue imaging and strain/strain rate are useful noninvasive tools for assess CRT.

Original languageEnglish (US)
Pages (from-to)545-548
Number of pages4
JournalFudan University Journal of Medical Sciences
Volume34
Issue number4
StatePublished - Jul 1 2007

Keywords

  • Cardiac resynchronization therapy
  • Doppler tissue imaging
  • Heart failure
  • Strain/ strain rate

ASJC Scopus subject areas

  • Medicine(all)

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