Abstract
Objective: To observe the value of quantitative arterial stiffness (QAS) and X-strain technique in assessment of changes for carotid artery elasticity in patients with systemic lupus erythematosus (SLE). Methods: Seventy-seven patients with SLE were divided into SLE 1 group (duration<5 years, n=46) and SLE 2 group (duration≥5 years, n=31). Forty healthy volunteers were enrolled as control group. Ultrasound, QAS and X-strain techique were performed to evaluate carotid arterial elastic function, and the parameters were compared among groups. Correlation of these parameters was analyzed. Results: There was no difference of intima-media thickness (IMT), elastic coefficient α, elastic coefficient β, pulse wave velocity nor augmentation index between control group and SLE 1 group (allP>0.05). The above parameters of SLE 2 group significantly increased compared with control group and SLE 1 group (all P<0.05). The maximum value of circumferential strain and circumferential strain rate were significantly different among three groups (all P<0.05), which decreased along with the course. IMT, QAS parameters and X-strain parameters were significantly correlated each other. Conclusion: QAS and X-strain technology can early detect changes of carotid arterial elasticity in SLE patients, which are important for prevention and intervention of cardiovascular events for SLE patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 386-389 |
| Number of pages | 4 |
| Journal | Chinese Journal of Medical Imaging Technology |
| Volume | 30 |
| Issue number | 3 |
| State | Published - Mar 2014 |
Keywords
- Carotid artery
- Lupus erythematosus, systemic
- Ultrasonography
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
- Physiology (medical)