Evidence-based prevention and surgical treatment of necrotizing enterocolitis-A review of randomized controlled trials

Mehul V. Raval, Nigel J. Hall, Agostino Pierro, R. Lawrence Moss*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

Necrotizing enterocolitis remains a common cause of morbidity and mortality in the neonatal period. Despite many advances in the management of the critically ill neonate, the exact etiology, attempts at prevention and determining best treatment for NEC have been elusive. Unfortunately, the overall survival for this poorly understood and complex condition has not improved. NEC is a condition that can and should be studied with randomized prospective trials (RCTs). This chapter reviews the current evidence-based trials for this condition thus far performed.

Original languageEnglish (US)
Pages (from-to)117-121
Number of pages5
JournalSeminars in Pediatric Surgery
Volume22
Issue number2
DOIs
StatePublished - May 2013

Keywords

  • Laparotomy
  • NECSTEPS trial
  • NEST trial
  • NET trial
  • Necrotizing enterocolitis
  • Peritoneal drainage
  • Randomized controlled trials

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery

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