EVIDENCE FOR ABNORMALITY OF BONE-MATRIX PROTEINS IN OSTEOGENESIS IMPERFECTA

Ian R. Dickson*, E. A. Millar, A. Veis

*Corresponding author for this work

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

Immunological and biochemical techniques demonstrated that the non-collagenous proteins of the organic matrix of bone were abnormal in quantity and composition in four children with osteogenesis imperfecta. This represents the main molecular difference found so far between bone in osteogenesis imperfecta and normal bone.

Original languageEnglish (US)
Pages (from-to)586-587
Number of pages2
JournalThe Lancet
Volume306
Issue number7935
DOIs
StatePublished - Sep 27 1975

ASJC Scopus subject areas

  • Medicine(all)

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