Evidence of a diurnal thermogenic handicap in obesity

Daniela Grimaldi; Federica Provini; Giulia Pierangeli; Natalia Mazzella; Giovanni Zamboni; Giulio Marchesini; Pietro Cortelli

doi:10.3109/07420528.2014.983603

Evidence of a diurnal thermogenic handicap in obesity

Daniela Grimaldi, Federica Provini, Giulia Pierangeli, Natalia Mazzella, Giovanni Zamboni, Giulio Marchesini, Pietro Cortelli^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

A thermogenic handicap has been proposed as potential contributor to weight gain in obese subjects but results from clinical studies are inconclusive. We tested whether diurnal and nocturnal body core temperature (BcT) measured for 20-h differed in nine obese subjects compared with 12 lean healthy controls when studied at rest under strictly controlled conditions. BcT was significantly reduced (∼0.35C) in obese subjects only during diurnal hours while during nocturnal hours BcT pattern was identical in the two groups. Our preliminary data indicate that obesity is associated with a diurnal thermogenic handicap which could play a role in favoring weight gain by lowering whole-body energy expenditure.

Original language	English (US)
Pages (from-to)	299-302
Number of pages	4
Journal	Chronobiology International
Volume	32
Issue number	2
DOIs	https://doi.org/10.3109/07420528.2014.983603
State	Published - Mar 1 2015

Keywords

Body core temperature
Energy expenditure
Obesity
Resting metabolic rate
Thermogenesis

ASJC Scopus subject areas

Physiology
Physiology (medical)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3109/07420528.2014.983603

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title = "Evidence of a diurnal thermogenic handicap in obesity",

abstract = "A thermogenic handicap has been proposed as potential contributor to weight gain in obese subjects but results from clinical studies are inconclusive. We tested whether diurnal and nocturnal body core temperature (BcT) measured for 20-h differed in nine obese subjects compared with 12 lean healthy controls when studied at rest under strictly controlled conditions. BcT was significantly reduced (∼0.35C) in obese subjects only during diurnal hours while during nocturnal hours BcT pattern was identical in the two groups. Our preliminary data indicate that obesity is associated with a diurnal thermogenic handicap which could play a role in favoring weight gain by lowering whole-body energy expenditure.",

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note = "Funding Information: The financial support of University of Bologna-Italy (Progetto Strategico Ateneo) is gratefully acknowledged. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. Publisher Copyright: {\textcopyright} 2014 Informa Healthcare USA, Inc.",

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AU - Provini, Federica

AU - Pierangeli, Giulia

AU - Mazzella, Natalia

AU - Zamboni, Giovanni

AU - Marchesini, Giulio

AU - Cortelli, Pietro

N1 - Funding Information: The financial support of University of Bologna-Italy (Progetto Strategico Ateneo) is gratefully acknowledged. The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. Publisher Copyright: © 2014 Informa Healthcare USA, Inc.

PY - 2015/3/1

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N2 - A thermogenic handicap has been proposed as potential contributor to weight gain in obese subjects but results from clinical studies are inconclusive. We tested whether diurnal and nocturnal body core temperature (BcT) measured for 20-h differed in nine obese subjects compared with 12 lean healthy controls when studied at rest under strictly controlled conditions. BcT was significantly reduced (∼0.35C) in obese subjects only during diurnal hours while during nocturnal hours BcT pattern was identical in the two groups. Our preliminary data indicate that obesity is associated with a diurnal thermogenic handicap which could play a role in favoring weight gain by lowering whole-body energy expenditure.

AB - A thermogenic handicap has been proposed as potential contributor to weight gain in obese subjects but results from clinical studies are inconclusive. We tested whether diurnal and nocturnal body core temperature (BcT) measured for 20-h differed in nine obese subjects compared with 12 lean healthy controls when studied at rest under strictly controlled conditions. BcT was significantly reduced (∼0.35C) in obese subjects only during diurnal hours while during nocturnal hours BcT pattern was identical in the two groups. Our preliminary data indicate that obesity is associated with a diurnal thermogenic handicap which could play a role in favoring weight gain by lowering whole-body energy expenditure.

KW - Body core temperature

KW - Energy expenditure

KW - Obesity

KW - Resting metabolic rate

KW - Thermogenesis

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Evidence of a diurnal thermogenic handicap in obesity

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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