Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons

Seth D. Goldstein; Todd E. Heaton; Alexander Bondoc; Roshni Dasgupta; Abdelhafeez Abdelhafeez; Andrew M. Davidoff; Timothy B. Lautz

doi:10.1016/j.jpedsurg.2020.10.013

Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons

Seth D. Goldstein, Todd E. Heaton, Alexander Bondoc, Roshni Dasgupta, Abdelhafeez Abdelhafeez, Andrew M. Davidoff, Timothy B. Lautz^*

^*Corresponding author for this work

Surgery

Research output: Contribution to journal › Review article › peer-review

Abstract

Fluorescence-guided surgery (FGS) is an increasingly available and popular method of visual field augmentation. The basic premise of FGS entails injection of fluorescent indocyanine green (ICG) and subsequent detection with a near-infrared (NIR) camera. For pediatric surgical oncologists, FGS remains experimental but is a promising modality for identifying tumor margins, locating metastases, performing sentinel lymph node biopsies, protecting peritumoral structures of interest, and facilitating reconstruction. Familiarity with basic ICG pharmacokinetics and NIR detection optics is critical for surgeons wishing to judiciously use FGS, as its success is firmly grounded in a thorough understanding of its capabilities and limitations. In this practical guide, we outline several well-described and innovative FGS applications by disease type, including their methods of administration, modes of detection, and typical ICG dosing paradigms. Level of Evidence: V

Original language	English (US)
Pages (from-to)	215-223
Number of pages	9
Journal	Journal of pediatric surgery
Volume	56
Issue number	2
DOIs	https://doi.org/10.1016/j.jpedsurg.2020.10.013
State	Published - Feb 2021

Keywords

Fluorescence
Indocyanine green
Metastasectomy
Sentinel lymph node

ASJC Scopus subject areas

Surgery
Pediatrics, Perinatology, and Child Health

Access to Document

10.1016/j.jpedsurg.2020.10.013

Fingerprint Dive into the research topics of 'Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons'. Together they form a unique fingerprint.

Cite this

@article{1394b47720494229b30d0a67b0960d9b,

title = "Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons",

abstract = "Fluorescence-guided surgery (FGS) is an increasingly available and popular method of visual field augmentation. The basic premise of FGS entails injection of fluorescent indocyanine green (ICG) and subsequent detection with a near-infrared (NIR) camera. For pediatric surgical oncologists, FGS remains experimental but is a promising modality for identifying tumor margins, locating metastases, performing sentinel lymph node biopsies, protecting peritumoral structures of interest, and facilitating reconstruction. Familiarity with basic ICG pharmacokinetics and NIR detection optics is critical for surgeons wishing to judiciously use FGS, as its success is firmly grounded in a thorough understanding of its capabilities and limitations. In this practical guide, we outline several well-described and innovative FGS applications by disease type, including their methods of administration, modes of detection, and typical ICG dosing paradigms. Level of Evidence: V",

keywords = "Fluorescence, Indocyanine green, Metastasectomy, Sentinel lymph node",

author = "Goldstein, {Seth D.} and Heaton, {Todd E.} and Alexander Bondoc and Roshni Dasgupta and Abdelhafeez Abdelhafeez and Davidoff, {Andrew M.} and Lautz, {Timothy B.}",

note = "Funding Information: The authors thank Nisha Badders for editorial assistance. Publisher Copyright: {\textcopyright} 2020 Elsevier Inc. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",

year = "2021",

month = feb,

doi = "10.1016/j.jpedsurg.2020.10.013",

language = "English (US)",

volume = "56",

pages = "215--223",

journal = "Journal of Pediatric Surgery",

issn = "0022-3468",

publisher = "W.B. Saunders Ltd",

number = "2",

}

Evolving applications of fluorescence guided surgery in pediatric surgical oncology : A practical guide for surgeons. / Goldstein, Seth D.; Heaton, Todd E.; Bondoc, Alexander; Dasgupta, Roshni; Abdelhafeez, Abdelhafeez; Davidoff, Andrew M.; Lautz, Timothy B.

In: Journal of pediatric surgery, Vol. 56, No. 2, 02.2021, p. 215-223.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Evolving applications of fluorescence guided surgery in pediatric surgical oncology

T2 - A practical guide for surgeons

AU - Goldstein, Seth D.

AU - Heaton, Todd E.

AU - Bondoc, Alexander

AU - Dasgupta, Roshni

AU - Abdelhafeez, Abdelhafeez

AU - Davidoff, Andrew M.

AU - Lautz, Timothy B.

PY - 2021/2

Y1 - 2021/2

N2 - Fluorescence-guided surgery (FGS) is an increasingly available and popular method of visual field augmentation. The basic premise of FGS entails injection of fluorescent indocyanine green (ICG) and subsequent detection with a near-infrared (NIR) camera. For pediatric surgical oncologists, FGS remains experimental but is a promising modality for identifying tumor margins, locating metastases, performing sentinel lymph node biopsies, protecting peritumoral structures of interest, and facilitating reconstruction. Familiarity with basic ICG pharmacokinetics and NIR detection optics is critical for surgeons wishing to judiciously use FGS, as its success is firmly grounded in a thorough understanding of its capabilities and limitations. In this practical guide, we outline several well-described and innovative FGS applications by disease type, including their methods of administration, modes of detection, and typical ICG dosing paradigms. Level of Evidence: V

AB - Fluorescence-guided surgery (FGS) is an increasingly available and popular method of visual field augmentation. The basic premise of FGS entails injection of fluorescent indocyanine green (ICG) and subsequent detection with a near-infrared (NIR) camera. For pediatric surgical oncologists, FGS remains experimental but is a promising modality for identifying tumor margins, locating metastases, performing sentinel lymph node biopsies, protecting peritumoral structures of interest, and facilitating reconstruction. Familiarity with basic ICG pharmacokinetics and NIR detection optics is critical for surgeons wishing to judiciously use FGS, as its success is firmly grounded in a thorough understanding of its capabilities and limitations. In this practical guide, we outline several well-described and innovative FGS applications by disease type, including their methods of administration, modes of detection, and typical ICG dosing paradigms. Level of Evidence: V

KW - Fluorescence

KW - Indocyanine green

KW - Metastasectomy

KW - Sentinel lymph node

UR - http://www.scopus.com/inward/record.url?scp=85096047024&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85096047024&partnerID=8YFLogxK

U2 - 10.1016/j.jpedsurg.2020.10.013

DO - 10.1016/j.jpedsurg.2020.10.013

M3 - Review article

C2 - 33189300

AN - SCOPUS:85096047024

VL - 56

SP - 215

EP - 223

JO - Journal of Pediatric Surgery

JF - Journal of Pediatric Surgery

SN - 0022-3468

IS - 2

ER -

Evolving applications of fluorescence guided surgery in pediatric surgical oncology: A practical guide for surgeons

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this