Evolving treatment strategies for inflammatory bowel disease

S. B. Hanauer*, T. Dassopoulos

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

41 Scopus citations

Abstract

Crohn's disease and ulcerative colitis are idiopathic inflammatory bowel diseases characterized by dysregulated intestinal immune responses in genetically susceptible hosts. Conventional approaches to the medical therapy of ulcerative colitis and Crohn's disease can now be directed at either induction or maintenance of remission to improve therapeutic efficacy while minimizing complications. Newer approaches have expanded the utility of conventional therapies by improving both safety and efficacy and highlight the importance of specific targets along the immunoinflammatory pathways. The combination of conventional and novel approaches now offers the potential of modifying the natural history of these diseases.

Original languageEnglish (US)
Pages (from-to)299-318
Number of pages20
JournalAnnual review of medicine
Volume52
DOIs
StatePublished - Mar 17 2001

Keywords

  • Biologic therapies
  • Crohn's disease
  • Infliximab
  • Ulcerative colitis

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint

Dive into the research topics of 'Evolving treatment strategies for inflammatory bowel disease'. Together they form a unique fingerprint.

Cite this