Abstract
Background: Psychosocial stressors increase the risks for cardiovascular disease across diverse populations. However, neighborhood level resilience resources may protect against poor cardiovascular health (CVH). This study used data from three CVH cohorts to examine longitudinally the associations of a resilience resource, perceived neighborhood social cohesion (hereafter referred to as neighborhood social cohesion), with the American Heart Association’s Life’s Simple 7 (LS7), and whether psychosocial stressors modify observed relationships. Methods: We examined neighborhood social cohesion (measured in tertiles) and LS7 in the Jackson Heart Study, Multi-Ethnic Study of Atherosclerosis, and Mediators of Atherosclerosis in South Asians Living in America study. We used repeated-measures, modified Poisson regression models to estimate the relationship between neighborhood social cohesion and LS7 (primary analysis, n = 6,086) and four biological metrics (body mass index, blood pressure, cholesterol, blood glucose; secondary analysis, n = 7,291). We assessed effect measure modification by each psychosocial stressor (e.g., low educational attainment, discrimination). Results: In primary analyses, adjusted prevalence ratios (aPR) and 95% confidence intervals (CIs) for ideal/intermediate versus poor CVH among high or medium (versus low) neighborhood social cohesion were 1.01 (0.97–1.05) and 1.02 (0.98–1.06), respectively. The psychosocial stressors, low education and discrimination, functioned as effect modifiers. Secondary analyses showed similar findings. Also, in the secondary analyses, there was evidence for effect modification by income. Conclusion: We did not find much support for an association between neighborhood social cohesion and LS7, but did find evidence of effect modification. Some of the effect modification results operated in unexpected directions. Future studies should examine neighborhood social cohesion more comprehensively and assess for effect modification by psychosocial stressors.
Original language | English (US) |
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Article number | 1890 |
Journal | BMC public health |
Volume | 22 |
Issue number | 1 |
DOIs | |
State | Published - Dec 2022 |
Funding
The authors thank the other investigators, the staff, and the participants of the JHS, MESA, and MASALA studies for their valuable contributions. The Mediators of Atherosclerosis in South Asians Living in America (MASALA) project described was supported by Grant Number R01HL093009 from the National Heart, Lung, And Blood Institute and the National Center for Research Resources and the National Center for Advancing Translational Sciences, National Institutes of Health, through UCSF-CTSI Grant Number UL1RR024131. The Multi-Ethnic Study of Atherosclerosis (MESA) study was supported by contracts 75N92020D00001, HHSN268201500003I, N01-HC-95159, 75N92020D00005, N01-HC-95160, 75N92020D00002, N01-HC-95161, 75N92020D00003, N01-HC-95162, 75N92020D00006, N01-HC-95163, 75N92020D00004, N01-HC-95164, 75N92020D00007, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168 and N01-HC-95169 from the National Heart, Lung, and Blood Institute, and by grants UL1-TR-000040, UL1-TR-001079, and UL1-TR-001420 from the National Center for Advancing Translational Sciences (NCATS). A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org . Research reported in this publication was supported by the National Heart, Lung, And Blood Institute of the National Institutes of Health under Award Number R01HL135200. 100% of the project costs are financed with Federal money. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.
Keywords
- Cardiovascular health
- Life’s simple 7
- Neighborhood
- Psychosocial factors
- Resilience
ASJC Scopus subject areas
- Public Health, Environmental and Occupational Health
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Examining relationships between perceived neighborhood social cohesion and ideal cardiovascular health and whether psychosocial stressors modify observed relationships among JHS, MESA, and MASALA participants
Dulin, A. J. (Creator), Park, J. W. (Creator), Scarpaci, M. M. (Creator), Dionne, L. A. (Creator), Sims, M. (Creator), Needham, B. L. (Creator), Fava, J. L. (Creator), Eaton, C. B. (Creator), Kanaya, A. M. (Creator), Kandula, N. R. (Creator), Loucks, E. B. (Creator) & Howe, C. J. (Creator), figshare, 2022
DOI: 10.6084/m9.figshare.c.6242855, https://springernature.figshare.com/collections/Examining_relationships_between_perceived_neighborhood_social_cohesion_and_ideal_cardiovascular_health_and_whether_psychosocial_stressors_modify_observed_relationships_among_JHS_MESA_and_MASALA_participants/6242855
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