Exchange Coupling in Soft Magnetic Nanostructures and Its Direct Effect on Their Theranostic Properties

Vikas Nandwana; Ruiying Zhou; Jeotikanta Mohapatra; Sungkyu Kim; Pottumarthi V. Prasad; J. P. Liu; Vinayak P. Dravid

doi:10.1021/acsami.8b09346

Exchange Coupling in Soft Magnetic Nanostructures and Its Direct Effect on Their Theranostic Properties

Vikas Nandwana, Ruiying Zhou, Jeotikanta Mohapatra, Sungkyu Kim, Pottumarthi V. Prasad, J. P. Liu, Vinayak P. Dravid^*

^*Corresponding author for this work

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Exchange coupling between hard and soft magnetic materials at the nanoscale exhibits novel or improved physical properties for energy and data storage applications. Recently, exchange coupling has also been explored in core/shell magnetic nanostructures (MNS) composed of hard and soft magnetic spinel ferrites, but applications have been limited in biomedicine due to the presence of "toxic" cobalt based ferrites as hard magnetic component. We report core/shell MNS where both core and shell components are soft magnetic ferrites (Fe₃O₄, MnFe₂O₄, and Zn_0.2Mn_0.8Fe₂O₄) and show that exchange coupling still exists due to the difference in their anisotropy. The physical properties (saturation magnetization, susceptibility, anisotropy, r₂ relaxivity, and specific absorption rate) of core/shell MNS are compared with the same size single phase counterparts which excludes any size dependent effect and gives the direct effect of exchange coupling. After optimization of core and shell components and their proportions, we have shown that a core/shell MNS shows significantly higher contrast enhancement and thermal activation properties than their single phase counterparts due to exchange coupling between core and shell ferrites. Our finding provides a novel way to improve theranostic properties of spinel ferrite based MNS while maintaining their biocompatibility.

Original language	English (US)
Pages (from-to)	27233-27243
Number of pages	11
Journal	ACS Applied Materials and Interfaces
Volume	10
Issue number	32
DOIs	https://doi.org/10.1021/acsami.8b09346
State	Published - Aug 15 2018

Funding

V.N. and V.P.D. gratefully acknowledge support from the NTU-NU Institute for NanoMedicine located at the International Institute for Nanotechnology, Northwestern University, USA, and the Nanyang Technological University, Singapore. The research related to oxide nanostructures was also supported by the National Science Foundation under Grant No. DMR-1507810. This work made use of the (EPIC, Keck-II, and SPID) facilities of the NUANCE Center at Northwestern University, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF NNCI-1542205); the MRSEC program (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; the State of Illinois, through the IIN. J.P.L and J.M. acknowledge support from the U.S. DoD/ARO under Grant W911NF-17-1-0529. V.N. and V.P.D. gratefully acknowledge support from the NTU-NU Institute for NanoMedicine located at the International Institute for Nanotechnology Northwestern University, USA, and the Nanyang Technological University Singapore. The research related to oxide nanostructures was also supported by the National Science Foundation under Grant No. DMR-1507810. This work made use of the (EPIC, Keck-II, and SPID) facilities of the NUANCE Center at Northwestern University, which has received support from the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF NNCI-1542205); the MRSEC program (NSF DMR-1720139) at the Materials Research Center; the International Institute for Nanotechnology (IIN); the Keck Foundation; the State of Illinois, through the IIN. J.P.L and J.M. acknowledge support from the U.S. DoD/ARO under Grant W911NF-17-1-0529.

Keywords

contrast enhancement
exchange coupling
magnetic nanostructures
theranostics
thermal activation

ASJC Scopus subject areas

General Materials Science

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Cite this

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abstract = "Exchange coupling between hard and soft magnetic materials at the nanoscale exhibits novel or improved physical properties for energy and data storage applications. Recently, exchange coupling has also been explored in core/shell magnetic nanostructures (MNS) composed of hard and soft magnetic spinel ferrites, but applications have been limited in biomedicine due to the presence of {"}toxic{"} cobalt based ferrites as hard magnetic component. We report core/shell MNS where both core and shell components are soft magnetic ferrites (Fe3O4, MnFe2O4, and Zn0.2Mn0.8Fe2O4) and show that exchange coupling still exists due to the difference in their anisotropy. The physical properties (saturation magnetization, susceptibility, anisotropy, r2 relaxivity, and specific absorption rate) of core/shell MNS are compared with the same size single phase counterparts which excludes any size dependent effect and gives the direct effect of exchange coupling. After optimization of core and shell components and their proportions, we have shown that a core/shell MNS shows significantly higher contrast enhancement and thermal activation properties than their single phase counterparts due to exchange coupling between core and shell ferrites. Our finding provides a novel way to improve theranostic properties of spinel ferrite based MNS while maintaining their biocompatibility.",

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Exchange Coupling in Soft Magnetic Nanostructures and Its Direct Effect on Their Theranostic Properties

Abstract

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