Excitatory Dysfunction Drives Network and Calcium Handling Deficits in 16p11.2 Duplication Schizophrenia Induced Pluripotent Stem Cell–Derived Neurons

Euan Parnell, Lorenza Culotta, Marc P. Forrest, Hiba A. Jalloul, Blair L. Eckman, Daniel D. Loizzo, Katherine K.E. Horan, Marc Dos Santos, Nicolas H. Piguel, Derek J.C. Tai, Hanwen Zhang, Tracy S. Gertler, Dina Simkin, Alan R. Sanders, Michael E. Talkowski, Pablo V. Gejman, Evangelos Kiskinis, Jubao Duan, Peter Penzes*

*Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

Neuroscience

Medicine and Dentistry